133116-83-3 Usage
Description
2-Fluoro-6-(trifluoromethyl)benzonitrile is an organic compound characterized by the presence of a fluorine atom at the 2nd position and a trifluoromethyl group at the 6th position on a benzene ring, with a nitrile functional group attached. This molecule is known for its unique chemical properties and reactivity, making it a valuable intermediate in various chemical reactions and synthesis processes.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-6-(trifluoromethyl)benzonitrile is used as a reagent in the synthesis of Quinolinecarboxamides, which are compounds with potential therapeutic applications in the treatment of autoimmune disorders. Its unique structure and reactivity contribute to the development of these bioactive molecules, offering new avenues for the management of autoimmune conditions.
Used in Chemical Synthesis:
2-Fluoro-6-(trifluoromethyl)benzonitrile may also be employed in various chemical synthesis processes, where its specific functional groups and reactivity can be utilized to produce a range of different compounds. Its versatility in chemical reactions makes it a valuable building block for the creation of new molecules with diverse applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 133116-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,1 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 133116-83:
(8*1)+(7*3)+(6*3)+(5*1)+(4*1)+(3*6)+(2*8)+(1*3)=93
93 % 10 = 3
So 133116-83-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F4N/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3H
133116-83-3Relevant articles and documents
Copper-catalyzed trifluoromethylation of aryl iodides with potassium (trifluoromethyl)trimethoxyborate
Knauber, Thomas,Arikan, Fatih,Roeschenthaler, Gerd-Volker,Goossen, Lukas J.
, p. 2689 - 2697 (2011)
Potassium (trifluoromethyl)trimethoxyborate is introduced as a new source of CF3 nucleophiles in copper-catalyzed trifluoromethylation reactions. The crystalline salt is stable on storage, easy to handle, and can be obtained in near-quantitative yields simply by mixing B(OMe)3, CF3SiMe3, and KF. The trifluoromethylation reagent allows the conversion of various aryl iodides into the corresponding benzotrifluorides in high yields under mild, base-free conditions in the presence of catalytic quantities of a CuI/1,10-phenanthroline complex.
