1349193-22-1

Basic information

• Product Name: 8-dibenzylamino-3,6-dioxaoctan-1-ol
• Synonyms: 8-dibenzylamino-3,6-dioxaoctan-1-ol
• CAS NO: 1349193-22-1
• Molecular Weight: 329.439
• Mol File: 1349193-22-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-dibenzylamino-3,6-dioxaoctan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-dibenzylamino-3,6-dioxaoctan-1-ol(1349193-22-1)
• EPA Substance Registry System: 8-dibenzylamino-3,6-dioxaoctan-1-ol(1349193-22-1)

Safety Data

• Hazardous Substances Data: 1349193-22-1(Hazardous Substances Data)

Upstream product

• 55-43-6 N-(2-chloroethyl)dibenzylamine hydrochloride 
• 111-46-6 diethylene glycol 
• 101-06-4 N,N-dibenzyl-2-aminoethanol 
• 136533-09-0 N,N-dibenzyl-5-amino-3-oxapentan-1-ol 
• 100-39-0 benzyl bromide 
• 455884-08-9 8-dibenzylamino-3,6-dioxaoctanoic acid ethyl ester 

Downstream Products

• 1349193-23-2 N-[N₁-(8-tert-butoxycarbonylamino-3,6-dioxaoct-1-yl)-1,2,3-triazol-4-yl]methyl-N-[N₄-(benzyloxycarbonyl)cytosin-1-ylacetyl]glycine ethyl ester 
• 1349193-24-3 N-[N₁-(8-tert-butoxycarbonylamino-3,6-dioxaoct-1-yl)-1,2,3-triazol-4-yl]methyl-N-[N₆-(benzyloxycarbonyl)adenin-9-ylacetyl]glycineethyl ester 
• 6338-55-2 2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol 
• 139115-92-7 tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)ethylcarbamate 
• 252881-74-6 tert-butyl 3-(2-(2-(2-aminoethoxyl)ethoxy)ethoxy)propanoate 
• 784105-33-5 3-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}propanoic acid 

Relevant articles and documents

Preparation method of amino polyethylene glycol propionic acid

The invention relates to the field of organic synthesis, in particular to a preparation method of amino polyethylene glycol propionic acid. The preparation method comprises the steps that catalytic hydrogenation is carried out on dibenzyl amino polyethylene glycol tert-butyl propionate shown in formula I-2 to obtain amino polyethylene glycol tert-butyl propionate shown in formula I-3; (2) the amino polyethylene glycol tert-butyl propionate shown in formula I-3 is hydrolyzed under the acidic condition to obtain amino polyethylene glycol propionic acid shown in formula I. The preparation methodof the amino polyethylene glycol propionic acid has the advantages that the defects in the prior art that the yield is low, the dangerousness is high, and the enlargement of production is difficult are overcome, the reaction conditions are mild, the operation is simple, an intermediate does not to be purified, the next reaction can be directly carried out, the whole yield reaches up to 87-92%, thepurity of end products reaches up to 97-99.5%, and a safe and efficient synthetic route is provided for the preparation of amino polyethylene glycol propionic acid.