13685-00-2

Basic information

• Product Name: (2-bromo-1-methoxyethyl)benzene
• Synonyms: (2-bromo-1-methoxyethyl)benzene;1-Phenyl-1-methoxy-2-bromoethane;Methyl(1-phenyl-2-bromoethyl) ether
• CAS NO: 13685-00-2
• Molecular Formula: C₉H₁₁BrO
• Molecular Weight: 215.08704
• EINECS: 237-200-4
• Mol File: 13685-00-2.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 232.3°C at 760 mmHg
• Flash Point: 98°C
• Appearance: /
• Density: 1.352g/cm³
• Vapor Pressure: 0.0902mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: (2-bromo-1-methoxyethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-1-methoxyethyl)benzene(13685-00-2)
• EPA Substance Registry System: (2-bromo-1-methoxyethyl)benzene(13685-00-2)

Safety Data

• Hazardous Substances Data: 13685-00-2(Hazardous Substances Data)

Usage

General Description

(2-bromo-1-methoxyethyl)benzene is a chemical compound with the molecular formula C9H11BrO, also known as bromoanisole. It is an organic compound that consists of a benzene ring with a bromine atom and a methoxyethyl group attached. This chemical is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also utilized as a solvent and intermediate in chemical reactions. (2-bromo-1-methoxyethyl)benzene is considered to be a flammable liquid and should be handled with care due to its potential hazards.

InChI:InChI=1/C9H11BrO/c1-11-9(7-10)8-5-3-2-4-6-8/h2-6,9H,7H2,1H3

Upstream product

• 100-42-5 styrene 
• 67-56-1 methanol 
• 37011-27-1 C₁₃H₁₇O₅Tl 
• 201230-82-2 carbon monoxide 
• 28078-73-1 methyl hypobromite 
• 89033-12-5 2-bromo-1-chloro-1-methoxy-ethane 

Downstream Products

• 4747-13-1 α-methoxystyrene 
• 3490-79-7 2-methoxy-2-phenylethan-1-amine 
• 109098-77-3 2-bromo-1-methoxy-1-(4-nitro-phenyl)-ethane 
• 54505-05-4 cyclohexyl-(β-methoxy-phenethyl)-amine 
• 104338-27-4 (β-methoxy-phenethyl)-methyl-amine 
• 6597-95-1 benzyl-(β-methoxy-phenethyl)-amine 
• 495-71-6 phenacylacetophenone 
• 93-55-0 1-phenyl-propan-1-one 
• 15982-59-9 2-methyl-1,4-diphenylbutane-1,4-dione 
• 116487-02-6 (+)-Neomenthyl 2-phenyl-2-methoxyethyl sulfide 

Relevant articles and documents

Alkene, Bromide, and ROH – How To Achieve Selectivity? Electrochemical Synthesis of Bromohydrins and Their Ethers

Bromohydrins and their ethers were electrochemically synthesized via hydroxy- and alkoxybromination of alkenes using potassium bromide and water or alcohols. High selectivity of bromohydrins formation was achieved only with the use of DMSO as the solvent and an acid as the additive. The proposed combination of starting reagents, additives, and solvents allowed to form bromohydrins or their ethers selectively despite the variety of side-products (epoxides, dibromides, diols). Bromohydrins were obtained in high yields, up to 96%, with a broad substrate scope in an undivided electrochemical cell equipped with glassy carbon and platinum electrodes at high current density. (Figure presented.).

Electrochemical Alkoxyhalogenation of Alkenes with Organohalides as the Halide Sources via Dehalogenation

A general, ideal atom utilization electrochemical technology to enable alkene alkoxyhalogenation and organohalide dehalogenation in one pot is presented. This technology is highlighted by convergent strategy integrating several reactions, such as alkene alkoxyhalogenation, organohalide dehalogenation, and dehalogenation deuteration. Experimental data suggest that alkenes have the lowest oxidation potential, which lead to anodic conversion of the C═C bond to the radical cation intermediates, and cathodic transformations of organohalides, including alkyl and aryl halides, as the nucleophilic halogen sources.

Synthesizing method of beta-bromo ether compound

The invention discloses a synthesizing method of a beta-bromo ether compound. The method specifically comprises the following steps: mixing a styrene compound which is as shown in formula I and is taken as a raw material, bromate intercalated zn-al hydrotalcite ZnAl-BrO3-LDHs and an alkali metal bromide compound; dissolving in an organic solvent; reacting for 1-4h at the temperature of 15-60 DEG C under the action of organic acid; obtaining a reaction solution after the reaction is finished; and separating and purifying to obtain the beta-bromo ether compound as shown in formula II. The method has the advantages of being high in bromine source stability, simple, easy to obtain, mild in reaction conditions, environmentally friendly, simple to operate and the like.