136863-23-5

Basic information

• Product Name: Benzenepropanol, 2-(hydroxymethyl)- (9CI)
• Synonyms: Benzenepropanol, 2-(hydroxymethyl)- (9CI)
• CAS NO: 136863-23-5
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• Product Categories: PHENYL
• Mol File: 136863-23-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanol, 2-(hydroxymethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanol, 2-(hydroxymethyl)- (9CI)(136863-23-5)
• EPA Substance Registry System: Benzenepropanol, 2-(hydroxymethyl)- (9CI)(136863-23-5)

Safety Data

• Hazardous Substances Data: 136863-23-5(Hazardous Substances Data)

Upstream product

• 14807-28-4 2-(3-oxopropyl)benzaldehyde 
• 447-53-0 1,2-Dihydronaphthalene 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 34288-40-9 2-(E)-[2-methoxycarbonylphenyl]acrylic acid methylester 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 25040-17-9 methyl 3-[2-(methoxycarbonyl)phenyl]propionate 
• 25705-34-4 2-(2-oxoethyl)benzaldehyde 
• 60-29-7 diethyl ether 
• 339367-21-4 11,12,13-Trioxa-tricyclo[8.2.1.0^2,7]trideca-2⁽⁷⁾,3,5-triene 
• 92864-91-0 Essigsaeure-<3-(2-acetoxymethylphenyl)propyl>ester 
• 776-79-4 2-(2-carboxyethyl)benzoic acid 

Downstream Products

• 65349-63-5 3-(2-Chloromethylphenyl)-propyl chloride 
• 5651-62-7 4,5-dihydrobenzo[c]oxepin-1-(3H)-one 
• 148433-03-8 2-(3-Hydroxypropyl)benzaldehyde 
• 175229-25-1 1,3,4,5-tetrahydrobenzo[c]oxepin-1-ol 
• 874332-88-4 C₃₁H₄₂N₄O₃ 
• 874334-13-1 C₃₁H₄₄N₄O₃ 
• 339177-03-6 3-(2-ethenylphenyl)propan-1-ol 
• 7216-22-0 2,3,4,5-tetrahydro-1H-benzo[c]azepine 
• 54311-89-6 2-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine 
• 54311-87-4 2-phenyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine 

Relevant articles and documents

Facile and simple synthesis of N -alkyl and N -aryl 2-benzazepines by nucleophilic heteroannulation

An efficient and practical synthesis of N-alkyl and N-aryl 2-benzazepine has been developed. The key steps involved in the synthesis were palladium-mediated Heck reaction followed by aza heterocyclic ring construction by nucleophilic heteroannulation. This four-step sequence synthetic protocol gave moderate to good yields for a wide range of substrates. Subsequently, functionalization of the synthesized compound was carried out under Heck and Suzuki reaction conditions.

Macrocyclic Modulators of the Ghrelin Receptor

The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective modulators of the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and variants thereof). Methods of synthesizing the novel compounds are also described herein. These compounds are useful as agonists of the ghrelin receptor and as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, central nervous system disorders, genetic disorders, hyperproliferative disorders and inflammatory disorders.

Copper-Catalyzed Cleavage of Unstrained C-C Bonds for the Synthesis of 1-Acyloxy-2,2,6,6-tetramethylpiperidines from Cyclic or Acyclic Ketones

A copper-catalyzed approach for the synthesis of 1-acyloxy-2,2,6,6-tetramethylpiperidines through the C-C bond cleavage of cyclic or acyclic ketones was developed. In this chemistry, a combination of CuCl 2 ·2H 2 O, 1,10-phenanthroline monohydrate, and aniline was crucial for the formation of the desired products by the reaction of ketones with TEMPO. This research provides a new strategy for the further transformation of α-aryl cyclic or acyclic ketones.