14097-24-6Relevant articles and documents
Microwave-assisted solid reaction: Reduction of ketones using sodium borohydride
Chen, Same-Ting
, p. 509 - 511 (1999)
A general and efficient procedure for microwave-assisted reduction of liquid and solid ketones using sodium borohydride without solvents is described. The added support can enhance both the efficiency and chemoselectivity of reduction.
Nickel-catalysed three-component connection reaction of a phenyl group, conjugated dienes, and aldehydes: Stereoselective synthesis of (E)-5-phenyl-3-penten-1-ols and (E)-3-methyl-5-phenyl-3-penten-1-ols
Shibata, Kazufumi,Kimura, Masanari,Kojima, Keisuke,Tanaka, Shuji,Tamaru, Yoshinao
, p. 348 - 353 (2001)
In the presence of 10 mol% of Ni(acac)2, Ph2Zn reacts with 1,3-butadiene and aldehydes at room temperature to give 1-alkyl and 1-aryl substituted (E)-5-phenyl-3-penten-1-ols (3) in good yields. Under similar conditions, the three components of Ph3BZnEt2, isoprene, and aldehydes combine with each other to furnish 1-alkyl and 1-aryl substituted (E)-3-methyl-5-phenyl-3-penten-1-ols (5) in good yields.
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Brewin,Turner
, p. 502 (1930)
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Asymmetric transfer hydrogenation of unsaturated ketones; factors influencing 1,4- vs 1,2- regio- and enantioselectivity, and alkene vs alkyne directing effects
Hall, Thomas H.,Adams, Hannah,Vyas, Vijyesh K.,Michael Chu,Wills, Martin
, (2020/12/07)
A detailed study has been completed on the asymmetric transfer hydrogenation (ATH) of a series of enones using Ru(II) catalysts. Electron-rich rings adjacent to the C[dbnd]O group reduce the level of C[dbnd]O reduction compared to C[dbnd]C. The ATH reaction can readily discriminate between double and triple bonds adjacent to ketones, reducing the double bond but leaving a triple bond intact in the major product.
Cobalt-Catalyzed Chemoselective Transfer Hydrogenative Cyclization Cascade of Enone-Tethered Aldehydes
Ma, Shuang-Shuang,Jiang, Biao-Ling,Yu, Zheng-Kun,Zhang, Suo-Jiang,Xu, Bao-Hua
supporting information, p. 3873 - 3878 (2021/05/26)
The ligand-free Co-catalyzed chemoselective reductive cyclization cascade of enone-tethered aldehydes with i-PrOH as the environmentally benign hydrogen surrogate is developed by this study. Mechanistic studies disclosed that such a protocol is initiated