1417516-10-9

Basic information

• Product Name: C₁₆H₁₃ClO
• Synonyms: C₁₆H₁₃ClO
• CAS NO: 1417516-10-9
• Molecular Weight: 256.732
• Mol File: 1417516-10-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₃ClO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₃ClO(1417516-10-9)
• EPA Substance Registry System: C₁₆H₁₃ClO(1417516-10-9)

Safety Data

• Hazardous Substances Data: 1417516-10-9(Hazardous Substances Data)

Upstream product

• 52807-27-9 4-chloro-2-iodo-1-methoxybenzene 
• 847267-25-8 ((5-chloro-2-methoxyphenyl)ethynyl)trimethylsilane 
• 624-31-7 4-tolyl iodide 
• 95186-47-3 4-chloro-2-ethynyl-1-methoxybenzene 

Downstream Products

• 55082-69-4 2-(4-methylphenyl)-3-phenyl-5-chlorobenzofuran 
• 1459800-70-4 5-chloro-2-(4-methylphenyl)-3-(phenylseleno)benzofuran 
• 1459800-67-9 5-chloro-2-(4-methylphenyl)-3-(phenylthio)benzofuran 

Relevant articles and documents

Synthesis of (Thio)Furan-Fused Phospholes via Phosphonation Cyclization and a Base-Promoted Phospha-Friedel-Crafts Reaction

Herein, we developed a novel strategy for synthesizing ladder (thio)furan-fused phospholes via intermolecular phosphonation cyclization and a base-promoted phospha-Friedel-Crafts reaction under mild conditions. The starting substrates are readily available phosphinic acids and easy-to-handle alkynes. The details of the reaction mechanism were further rationalized using theoretical calculations. This protocol can be widely applied to synthesize furan- and thiofuran-fused phospholes as well as the corresponding large π-extended derivatives, which are of great interest in the domain of organic functional materials.