95186-47-3

Basic information

• Product Name: 4-chloro-2-ethynyl-1-methoxybenzene
• Synonyms: 4-chloro-2-ethynyl-1-methoxybenzene
• CAS NO: 95186-47-3
• Molecular Formula: C₉H₇ClO
• Molecular Weight: 166.61
• Mol File: 95186-47-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-2-ethynyl-1-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-ethynyl-1-methoxybenzene(95186-47-3)
• EPA Substance Registry System: 4-chloro-2-ethynyl-1-methoxybenzene(95186-47-3)

Safety Data

• Hazardous Substances Data: 95186-47-3(Hazardous Substances Data)

Upstream product

• 60633-25-2 2-bromo-4-chloroanisole 
• 847267-25-8 ((5-chloro-2-methoxyphenyl)ethynyl)trimethylsilane 
• 7035-09-8 5-chloro-2-methoxybenzaldehyde 
• 95186-46-2 4-chloro-2-<2',2'-dibromoethenyl>-anisol 

Downstream Products

• 1427034-43-2 4-chloro-2-(4-fluoro-1H-indol-2-yl)phenol 
• 1426960-44-2 5-(11-fluoro-6H-benzo[5,6][1,3]oxazino[3,4-a]indol-2-yl)-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide 
• 1417516-10-9 C₁₆H₁₃ClO 
• 1242137-84-3 4-chloro-2-[(4-fluorophenyl)ethynyl]-1-methoxybenzene 
• 1191950-69-2 4-chloro-1-methoxy-2-(phenylethynyl)benzene 
• 3261-05-0 5-chlorobenzofuran-3(2H)-one 

Relevant articles and documents

Halogen-Mediated Cascade Cyclization Reaction of Aryldiynes to Indeno[1,2-c]chromene Derivatives

The halogen-mediated cyclization reaction of aryldiynes to produce halogenated indeno[1,2-c]chromene derivatives is described. Treatment of aryldiynes 1 with one equivalent of iodine gave iodinated indeno[1,2-c]chromenes 3 in good chemical yields. When two equivalents of iodine were employed into the reaction mixture, dimer 9 was obtained as the major products. On the other hand, reaction of two equivalents of CuBr2 with compounds 1 gave the brominated indeno[1,2-c]chromenes 4. The DFT calculation of the iodine-mediated cyclization reactions for molecules containing methoxy, carboxy, amino, and sulfide substituents were carried out in order to understand how the substituent affects the cyclization pathway.

TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE

The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide.