14547-83-2

Basic information

• Product Name: 4-bromo-N-pyridin-2-ylbenzamide
• Synonyms: 4-bromo-N-pyridin-2-ylbenzamide;4-BROMO-N-2-PYRIDINYL-BENZAMIDE;BENZAMIDE, 4-BROMO-N-2-PYRIDINYL-;4-bromo-N-(pyridin-2-yl)benzamide(WXC05761)
• CAS NO: 14547-83-2
• Molecular Formula: C₁₂H₉BrN₂O
• Molecular Weight: 277.12
• Mol File: 14547-83-2.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-bromo-N-pyridin-2-ylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-N-pyridin-2-ylbenzamide(14547-83-2)
• EPA Substance Registry System: 4-bromo-N-pyridin-2-ylbenzamide(14547-83-2)

Safety Data

• Hazardous Substances Data: 14547-83-2(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 34658-66-7 2-(4-bromophenyl)imidazo[1,2-a]pyridine 
• 1585-07-5 1-bromo-4-ethylbenzene 
• 588-93-2 p-bromo-n-propylbenzene 
• 41492-05-1 p-bromobutylbenzene 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 15226-74-1 dicobalt octacarbonyl 
• 589-87-7 1,4-bromoiodobenzene 
• 99-73-0 para-bromophenacyl bromide 
• 106-38-7 para-bromotoluene 
• 35578-47-3 4,4'-dibromobenzil 
• 5391-88-8 1-(4-bromophenyl)ethanol 
• 4981-64-0 1-(4-bromophenyl)-1-butanone 
• 10342-83-3 4'-Bromopropiophenone 

Downstream Products

• 850568-25-1 4-(pyridin-2-yl-aminocarbonyl)benzeneboronic acid 
• 1420478-89-2 (S)-2-((1-(4-(pyridin-2-ylcarbamoyl)phenyl)-8-amino)imidazole[1,5-a]pyrazin-2-yl)pyrrolidine1-yl-carboxylic acid benzyl ester 
• 1419221-81-0 benzyl (3R)-3-(8-amino-1-(4-[(pyridin-2-yl)carbamoyl]phenyl)imidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate 

Relevant articles and documents

A dual chemosensor for Cu2+and Fe3+based on π-extend tetrathiafulvalene derivative

A new dual chemosensor (TTF-PBA) for Fe3+and Cu2+in different signal pathways was designed and synthesized. The absorption spectrum, fluorescence spectrum and cyclic voltammograms changed in the presence of Cu2+and Fe3+. The optical color changed within 5?s from yellow to orange upon the addition of Cu2+, and it changed to dark yellow when Fe3+existed. The cyclic voltammogram of Cu2+/TTF-PBA changed from Eox?=?0.50?V, Ered?=?0.32?V to Eox?=?0.64?V, Ered?=?0.80?V (vs Ag/AgCl) upon the addition of 2.0 equiv. Cu2+. As for Fe3+/TTF-PBA, its oxidation wave disappeared, and its reduction wave appeared at Ered?=??0.59?V (vs Ag/AgCl) upon the addition of 4.0 equv. Fe3+. The sensor displayed high selectivity for Cu2+and Fe3+over other ions including Pb2+, Zn2+, Ni2+, Ag+, Cr3+, Mn2+, Al3+, Co2+, Pd2+, Hg2+, Fe2+Cd2+, Ce3+, Bi3+and Au3+, the detection limits for Cu2+and Fe3+ion reached as low as 5.33?×?10?7?mol/L and 5.34?×?10?7?mol/L, respectively. Furthermore, when Fe3+existed, Cu2+can be detected sequentially by the sensor through the absorption spectrum and the color change observed by naked-eyes.

Co2(CO)8as a Solid CO (g) Source for the Amino Carbonylation of (Hetero)aryl Halides with Highly Deactivated (Hetero)arylamines

Carbonylation of (hetero)aryl iodides/bromides with highly deactivated 2-aminopyridines using Pd-Co(CO)4 bimetallic catalysis is accomplished. The use of Co2(CO)8 as a solid CO(g) source enhanced reaction rates observed when compared to CO(g), and excellent yields highlight the versatility of the developed protocol. A wide range of electronically and sterically demanding heterocyclic amines and (hetero)aryl iodides/bromides employed for this study resulted in excellent yields of amino carbonylated products. The developed methodology was further extended to synthesize Trypanosome brucie and luciferase inhibitors.

Copper(I)-catalysed aerobic oxidative selective cleavage of C[sbnd]C bond with DMAP: Facile access to N-substituted benzamides

A base/DMAP system for efficient oxidative cleavage of C(CO)–C(alkyl) bond to generate N-substituted benzamides has been developed in the presence of copper(I) chloride. The usage of inexpensive copper catalyst, broad substrate scope, mild conditions make