15163-59-4Relevant articles and documents
Exploiting a silver-bismuth hybrid material as heterogeneous noble metal catalyst for decarboxylations and decarboxylative deuterations of carboxylic acids under batch and continuous flow conditions
?tv?s, Sándor B.,Fül?p, Ferenc,Kónya, Zoltán,Kukovecz, ákos,Márton, András,Mészáros, Rebeka,Pálinkó, István,Szabados, Márton,Varga, Gábor
, p. 4685 - 4696 (2021/07/12)
Herein, we report novel catalytic methodologies for protodecarboxylations and decarboxylative deuterations of carboxylic acids utilizing a silver-containing hybrid material as a heterogeneous noble metal catalyst. After an initial batch method development, a chemically intensified continuous flow process was established in a simple packed-bed system which enabled gram-scale protodecarboxlyations without detectable structural degradation of the catalyst. The scope and applicability of the batch and flow processes were demonstrated through decarboxylations of a diverse set of aromatic carboxylic acids. Catalytic decarboxylative deuterations were achieved on the basis of the reaction conditions developed for the protodecarboxylations using D2O as a readily available deuterium source.
Method for synthesizing 3,4-difluoro-2'-aminobiphenyl
-
Paragraph 0089; 0090; 0102; 0103, (2018/03/28)
The invention relates to a method for synthesizing 3,4-difluoro-2'-aminobiphenyl. The method comprises: carrying out a reaction on o-nitrobenzoic acid, an alkali and a solvent, removing the water, adding substituted halobenzene, a catalyst and a ligand, c
Arylalkene synthesis via decarboxylative cross-coupling of alkenyl halides
Tang, Jie,Goossen, Lukas J.
supporting information, p. 2664 - 2667 (2014/06/09)
A bimetallic catalyst system generated from readily available palladium(II) and copper(I) salts, 1,10-phenanthroline and tri-1-naphthylphosphine was found to efficiently mediate the decarboxylative cross-coupling of alkenyl bromides and chlorides with aromatic carboxylates. It allows the regiospecific synthesis of a broad range of aryl- and heteroarylalkenes in high yields.