15512-06-8

Basic information

• Product Name: 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL
• Synonyms: 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL
• CAS NO: 15512-06-8
• Molecular Formula: C₁₄H₂₂O₂
• Molecular Weight: 222.32
• Mol File: 15512-06-8.mol
• Article Data: 16

Chemical Properties

• Melting Point: 83-84 °C(Solv: isooctane (540-84-1))
• Boiling Point: 151.5-154 °C(Press: 10 Torr)
• Appearance: /
• Density: 1.012±0.06 g/cm3(Predicted)
• PKA: 10.99±0.15(Predicted)
• CAS DataBase Reference: 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL(15512-06-8)
• EPA Substance Registry System: 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL(15512-06-8)

Safety Data

• Hazardous Substances Data: 15512-06-8(Hazardous Substances Data)

Usage

Description

3,6-Di-tert-butyl-benzene-1,2-diol, also known as 3,6-di-tert-butylcatechol, is an organic compound with the molecular formula C14H24O2. It is a di-tert-butyl substituted catechol, which is a type of phenol. 3,6-DI-TERT-BUTYL-BENZENE-1,2-DIOL is characterized by its two hydroxyl groups attached to a benzene ring, with two tert-butyl groups providing steric hindrance. Its chemical structure endows it with various biological properties and potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
3,6-Di-tert-butyl-benzene-1,2-diol is used as an intermediate in the synthesis of 3,6-di-tert-butyl-o-benzoquinone (D428030) for its anti-tumoral properties. This quinone derivative is known to possess a number of biological properties, making it a promising candidate for the development of new drugs targeting cancer cells.
Used in Antimicrobial Applications:
3,6-Di-tert-butyl-o-benzoquinone, synthesized from 3,6-di-tert-butylcatechol, is used as an antimicrobial agent. Its ability to inhibit the growth of various microorganisms makes it a valuable compound in the development of new antibiotics and antifungal agents.
Used in Cardiovascular Disease Prevention:
3,6-Di-tert-butyl-o-benzoquinone, derived from 3,6-di-tert-butylcatechol, is also known for its potential in preventing and treating cardiovascular diseases. Its anti-inflammatory and antioxidant properties contribute to its effectiveness in managing and reducing the risk of heart-related conditions.

Upstream product

• 34105-76-5 3,5-di-tert-butyl-1,2-benzoquinone 
• 120-80-9 benzene-1,2-diol 
• 75-65-0 tert-butyl alcohol 
• 45985-24-8 TEMPOL 
• 115-11-7 isobutene 
• 504-63-2 trimethyleneglycol 
• 1197-19-9 4-cyano-N,N-dimethylaniline 
• 929207-99-8 3,6-di(tert-butyl)-2-[N-(4-cyanophenyl)-N-methylamino]methoxyphenol 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 2444-28-2 2,6-di-tert-butyl-4-hydroxyphenol 
• 67-64-1 acetone 
• 42473-26-7 3,6-di-tert-butyl-2-hydroxyphenoxyl 
• 1020-31-1 3,5-Di-tert-butylcatechol 

Downstream Products

• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 67341-93-9 bis(3,6-di-tert-butylphenylene-1,2-dihydroxy)-2-hydroxy-3,6-di-tert-butylphenoxyphosphorane 
• 42473-26-7 3,6-di-tert-butyl-2-hydroxyphenoxyl 
• 93378-35-9 3,6-Di-tert-butyl-2-(4,7-di-tert-butyl-benzo[1,3]dioxol-2-yloxy)-phenol 
• 1020-31-1 3,5-Di-tert-butylcatechol 
• 98-19-1 5-tert-Butyl-m-xylene 
• 34105-76-5 3,5-di-tert-butyl-1,2-benzoquinone 
• 23803-85-2 2,5-di-tert-butyl-6-hydroxy-1,4-benzoquinone 
• 93378-36-0 2',4,5',7-tetra-tert-butyl-3'-hydroxy-3a,7a-dihydrospiro(benzo-1,3-dioxol-2,1'-cyclohexa[2,5]diene)-4'-one 
• 63488-44-8 5,6-dibromo-3-tert-butylpyrocatechol 
• 87418-61-9 4-Bromo-3,6-di-tert-butyl-[1,2]benzoquinone 
• 80284-14-6 3,6-di-tert-butyl-4-chlorocyclohexa-3,5-diene-1,2-dione 
• 80284-16-8 6-tert-Butyl-3,4-dichloro-[1,2]benzoquinone 
• 106002-59-9 5,6-dichloro-3,6-di-tert-butyl-3-cyclohexene-1,2-dione 

Relevant articles and documents

Novel oxidation reactions of sterically demanding 3,6-di-tert-butyl porphyrin-o-quinones to muconic anhydride derivatives

Porphyrin quinones with sterically demanding 3,6-di-tert-butyl-o-quinones were synthesized for electron transfer studies. In the presence of atmospheric oxygen the covalently free base porphyrin-o-quinones are oxidized to muconic acid anhydride and 3,6-di

MIGRATION OF ALKYL GROUPS OF o-tert-BUTYL-SUBSTITUTED HYDROXYAROMATIC COMPOUNDS UNDER HIGH PRESSURE IN COMBINATION WITH SHEARING STRESS

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Heterospin biradicals based on new piperidineoxyl-substituted 3,6-di-tert-butyl-o-benzoquinone

A nucleophilic addition reaction of 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (OH-TEMPO) to 3,6-di-tert-butyl-o-benzoquinone was used to obtain a new sterically hindered o-benzoquinone (1) containing 2,2,6,6-tetramethylpiperidineoxyl functional group, which was characterized by IR spectroscopy, mass spectrometry, elemental analysis, and X-ray diffraction. A one-electron reduction of 1 with potassium and thallium is an efficient method for the generation of earlier unknown heterospin biradicals 5a and 5b, respectively, containing nitroxide and o-semiquinone radical centers. Analysis of the hyperfine structure of the ESR spectra of biradicals 5a and 5b in solution showed that they belong to the group of heterospin biradicals with strong (J >> a) and fast exchange interaction between the radical centers.

Alkoxylation of 3,6-Di-tert-butyl-1,2-benzoquinone. New Bis-1,2-benzoquinones

Alkoxylation of 3,6-di-tert-butyl-1,2-benzoquinone with a number of diols, including propane-1,3- diol, butane-1,4-diol, di-, and triethylene glycols, and cyclohexane-1,4-diyldimethanol, was studied. Nine new 4-alkoxy-3,6-di-tert- butyl-1,2-benzoquinones were synthesized, four of which were bis-1,2-benzoquinones with different tethers (6-13 atoms) between the quinone fragments. Depending on the length of the chain between the hydroxy groups in glycols, bicyclic 4,5-disubstituted 3,6-di-tert-butyl-1,2-benzoquinones were formed or their stepwise alkoxylation occurred. The newly synthesized o-benzoquinone derivatives can be reduced with alkali metals to give radical anions and converted into semiquinone chelates with manganese carbonyl. Pleiades Publishing, Ltd., 2011.