158817-23-3

Basic information

• Product Name: (2R,3R)-5-p-methoxybenzyloxy-3-methylpentane-1,2-diol
• Synonyms: (2R,3R)-5-p-methoxybenzyloxy-3-methylpentane-1,2-diol
• CAS NO: 158817-23-3
• Molecular Weight: 254.326
• Mol File: 158817-23-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2R,3R)-5-p-methoxybenzyloxy-3-methylpentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-5-p-methoxybenzyloxy-3-methylpentane-1,2-diol(158817-23-3)
• EPA Substance Registry System: (2R,3R)-5-p-methoxybenzyloxy-3-methylpentane-1,2-diol(158817-23-3)

Safety Data

• Hazardous Substances Data: 158817-23-3(Hazardous Substances Data)

Upstream product

• 142860-83-1 1-(4-methoxybenzyloxy)-3-butene 
• 201667-72-3 methyl (2E)-5-(4-methoxybenzyloxy)-2-pentenoate 
• 135362-69-5 3-(4-methoxybenzyl)oxypropan-1-ol 
• 146986-42-7 ((2S,3S)-3-(2-(4-methoxybenzyloxy)ethyl) oxiran-2-yl)methanol 
• 158817-21-1 (E)-5-(4-methoxybenzyloxy)pent-2-en-1-ol 
• 123-11-5 4-methoxy-benzaldehyde 
• 128461-65-4 3-(p-methoxybenzyloxy)propanal 
• 75-24-1 trimethylaluminum 
• 5689-71-4 2-(4-methoxy-phenyl)-[1,3]dioxane 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 158817-28-8 (2S,3S,4R,7R)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-9-(4-methoxy-benzyloxy)-3,7-dimethyl-non-5-yn-4-ol 
• 201667-83-6 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-[1'',2''-dimethyl-3''-hydroxy-4''-(2,4,6-triisopropylbenzenesulfonyloxy)butyl]-1,3-dioxane 
• 201667-81-4 (4R,5S,6S)-4-[(1S,2S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-5-(4-methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxane 
• 201667-93-8 (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one 
• 201667-84-7 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3''-hydroxy-5''-hexynyl)-1,3-dioxane 
• 158817-34-6 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3''-hydroxy-5''-hexenyl)-1,3-dioxane 
• 201667-82-5 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3'',4''-dihydroxybutyl)-1,3-dioxane 
• 158817-33-5 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3'',4''-epoxybutyl)-1,3-dioxane 
• 158817-22-2 Benzoic acid (Z)-(1S,4R)-1-[(1S,2S)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-6-(4-methoxy-benzyloxy)-4-methyl-hex-2-enyl ester 

Relevant articles and documents

Total synthesis of two γ-butyrolactone containing compounds (Z,11S)-3,4-trans-11-hydroxy-3-methyldodec-cis-6-en-4-olide and (Z)-3,4-trans-11-oxo-3-methyldodec-cis-6-en-4-olide

The first total synthesis of (Z,11S)-3,4-trans-11-hydroxy-3-methyldodec-cis-6-en-4-olide and (Z)-3,4-trans-11-oxo-3-methyldodec-cis-6-en-4-olide was accomplished using Jacobsen hydrolytic kinetic resolution, Ohira-Bestmann reaction, regioselective alkyne

InCl3-mediated intramolecular Friedel-Crafts-type cyclization and its application to construct the [6-7-5-6] tetracyclic scaffold of liphagal

A unified strategy toward the construction of the [5.7.6]tricyclic skeleton of liphagal is reported, featuring InCl3-mediated intramolecular Friedel-Crafts-type cyclization.

Palladium-catalyzed couplings to nucleophilic heteroarenes: The total synthesis of (-)-frondosin B

The total synthesis of (-)-frondosin B, the enantiomer of naturally-occuring (+)-frondosin B, is described, wherein a palladium-catalyzed cyclization is used to establish the tetracyclic ring system of the natural product. Graphical Abstract.