1613226-33-7Relevant articles and documents
One pot synthesis of new heterocyclic systems: Polysubstituted pyrano[3,2-c]chromene and benzo[g]chromene derivatives
Nasri, Shima,Bayat, Mohammad
, p. 77 - 83 (2018/05/03)
A novel library of pyrano[3,2-c]chromene-3-carbonitrile and benzo[g]chromene-3-carbonitrile containing an aroyl or acetyl group moiety at 4-position has been extended by successive three-component reaction of 4-hydroxycoumarin or 2-hydroxy-1,4-naphthoquinone with phenylglyoxal monohydrate and a CH-acid like malononitrile/ethyl cyanoacetate/methyl cyanoacetate/cyanoacetamide under mild condition in ethanol. This approach for the preparation of novel polysubstituted pyrano[3,2-c]chromene and benzo[g]chromene is distinguished with high atom-economy, good to high efficiencies, mild and metal-free conditions, simple workup and easy purification.
One-pot synthesis of novel pyrano-fused coumarins catalyzed by zinc oxide nanoparticles
Khodabakhshi, Saeed,Karami, Bahador,Eskandari, Khalil
, p. 1670 - 1677 (2014/07/08)
A new class of pyrano[3,2-c]coumarins containing an aryloylgroup was synthesized via the three-component reactions of 4-hydroxycoumarin with arylglyoxals and malononitrile. The reactions are efficiently catalyzed by zinc oxide nanoparticles as powerful and recyclable catalyst. The green chemistry principles were also considered and the present method has some advantages, such as simplicity, low catalyst loading, and high yields.
A new three-component coupling reaction of aryl glyoxal, malononitrile, and 4-hydroxy coumarin catalysed by recyclable TiO2 nanoparticles
Khodabakhshi, Saeed,Shahamirian, Mozhgan,Baghernejad, Mojtaba
, p. 473 - 476 (2014/10/16)
Aryl glyoxals reacted with malononitrile and 4-hydroxycoumarin in the presence of a catalytic amount of TiO2 nanoparticles to give a hitherto unknown family of pyranochromenes in up to 80% yield. This new three-component reaction yielded some novel pyrano[3,2-c]chromene-5-ones containing an aroyl substituent. Using a recyclable and safe catalyst along with a green solvent system made the process eco-friendly and economic.