1622923-36-7 Usage
Description
(Ethylthiotrifluoroborate)methane dimethyliminium zwitterion is a unique chemical compound characterized by its zwitterionic structure, which consists of both positive and negative charges within the same molecule. This feature contributes to its distinct properties and potential applications in various fields.
Uses
Used in Chemical Synthesis:
(Ethylthiotrifluoroborate)methane dimethyliminium zwitterion is used as a reagent for the preparation of potassium acyltrifluoroborates (KAT's). Its benchtop stability and solid-state nature make it a reliable choice for this application. The synthesis process involves the use of 1.0 equivalent of n-BuLi (in hexane) at -78°C from the corresponding aryl/heteroaryl halide, resulting in KAT's that can be isolated without the need for column chromatography.
Used in Pharmaceutical Industry:
(Ethylthiotrifluoroborate)methane dimethyliminium zwitterion may also find applications in the pharmaceutical industry, potentially serving as a building block or intermediate for the development of new drugs. Its zwitterionic nature could be exploited to enhance the solubility, bioavailability, or target specificity of certain drug candidates.
Used in Material Science:
The unique properties of (ethylthiotrifluoroborate)methane dimethyliminium zwitterion may also be harnessed in the field of material science. Its zwitterionic structure could be utilized to develop novel materials with specific properties, such as improved conductivity, enhanced stability, or tailored interactions with other molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1622923-36-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,2,9,2 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1622923-36:
(9*1)+(8*6)+(7*2)+(6*2)+(5*9)+(4*2)+(3*3)+(2*3)+(1*6)=157
157 % 10 = 7
So 1622923-36-7 is a valid CAS Registry Number.
1622923-36-7Relevant articles and documents
A reagent for the one-step preparation of potassium acyltrifluoroborates (KATs) from aryl- and heteroarylhalides
Eroes, Gabor,Kushida, Yo,Bode, Jeffrey W.
supporting information, p. 7604 - 7607 (2014/08/05)
Potassium acyltrifluoroborates (KATs) are fascinating functional groups whose further exploration is limited by poor synthetic access. Documented herein is the design and synthesis of a new reagent for their one-step preparation from aryl- and heteroarylhalides. The reagent is a stable, soluble zwitterion prepared by S-alkylation of a novel thioformamide trifluoroboronate. The KATs are prepared by adding one equivalent of nBuLi to a mixture of the aryl halide and the reagent at -78 C. This protocol is suitable for the preparation of KATs containing pyridines, esters, nitro groups, and halides.
