169498-29-7

Basic information

• Product Name: (R)-1-[3-(1-benzyloxycarbonyl-4-piperidyl)propionyl]-3-piperidinecarboxylic acid
• CAS NO: 169498-29-7
• Molecular Weight: 402.491
• Mol File: 169498-29-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-1-[3-(1-benzyloxycarbonyl-4-piperidyl)propionyl]-3-piperidinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-[3-(1-benzyloxycarbonyl-4-piperidyl)propionyl]-3-piperidinecarboxylic acid(169498-29-7)
• EPA Substance Registry System: (R)-1-[3-(1-benzyloxycarbonyl-4-piperidyl)propionyl]-3-piperidinecarboxylic acid(169498-29-7)

Safety Data

• Hazardous Substances Data: 169498-29-7(Hazardous Substances Data)

Upstream product

• 163343-71-3 (R)-piperidine-3-carboxylic acid ethyl ester*l-tartaric acid 
• 51052-79-0 3-(4-piperidinyl)propionic acid hydrochloride 
• 63845-33-0 1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid 
• 25137-01-3 (R)-ethyl nipecotate 
• 5337-79-1 3-(4-pyridinyl)-2-propenoic acid 
• 1822-32-8 3-(4-piperidyl)propionic acid 
• 71962-74-8 Ethyl nipecotate 

Downstream Products

• 198958-88-2 [S-(R*,S*)]-β-[[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridine propanoic acid 

Relevant articles and documents

A Practical Synthesis of the Platelet Fibrinogen Antagonist, Elarofiban

Elarofiban is a novel, nonpeptide, orally active fibrinogen receptor antagonist useful for the treatment of platelet mediated thrombotic disorders (Costanzo, M. J.; Hoekstra, W. J.; Maryanoff, B. E. WO, 97/41102,1997). Herein we describe the process research that was carried out for the synthesis of elarofiban that eventually led to the development of a safe and cost-effective commercial scale process.