171777-72-3 Usage
Description
Folic Acid-D4 is a labeled vitamer of folic acid, which is a vital nutrient required for various biological processes. It is a yellow solid and is known for its role in synthesizing DNA, conducting DNA repair, and methylating DNA. Additionally, it acts as a cofactor in biological reactions involving folate.
Uses
Used in Pharmaceutical Industry:
Folic Acid-D4 is used as an internal standard for stable isotope dilution assays, which are essential in the pharmaceutical industry for accurate quantification of drugs and their metabolites in biological samples.
Used in Biotechnology and Research:
Folic Acid-D4 is used as a vitamin needed to synthesize DNA, conduct DNA repair, and methylate DNA in various biotechnological and research applications. Its role in these processes makes it a crucial component in the study of genetic and cellular functions.
Used in Diagnostics:
As a labeled vitamer of folic acid, Folic Acid-D4 is utilized in diagnostic assays to detect and measure the levels of folic acid in biological samples, which can be crucial for assessing the nutritional status and diagnosing related deficiencies or conditions.
Used in Nutritional Supplements:
Folic Acid-D4 is also used in the development of nutritional supplements, particularly those aimed at supporting DNA synthesis, repair, and methylation, as well as overall folate metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 171777-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,7,7 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 171777-72:
(8*1)+(7*7)+(6*1)+(5*7)+(4*7)+(3*7)+(2*7)+(1*2)=163
163 % 10 = 3
So 171777-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C2H4O2.CH4N2/c1-2(3)4;2-1-3/h1H3,(H,3,4);1H,(H3,2,3)/i;1+1
171777-72-3Relevant articles and documents
Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays
Freisleben, Achim,Schieberle, Peter,Rychlik, Michael
, p. 4760 - 4768 (2002)
[2H4]Folic acid was synthesized by deuterating p-aminobenzoic acid, which was then coupled to glutamic acid and 6-formylpterin, Using [2H4]folic acid as starting component enabled the preparation of labeled vitamers tetrahydrofolate, 5-formyltetrahydrofolate, 5-methyltetrahydrofolate, and 10-formylfolate which were characterized by electrospray mass spectrometry and collision-induced dissociation. The mass spectrometric studies confirmed that the compounds could be used as internal standards in stable isotope dilution assays.
