1719-53-5 Usage
Description
Dichlorodiethylsilane is a colorless liquid with a pungent odor, characterized by its corrosive nature towards metals and tissue. It has a flash point of 77°F, and its vapors are heavier than air. Dichlorodiethylsilane is primarily used as an intermediate for the production of silicones and finds applications in various industries, including organic synthesis, pharmaceuticals, agrochemicals, and dyes.
Uses
1. Silicone Industry:
Dichlorodiethylsilane is used as an intermediate for the production of silicones due to its chemical properties that facilitate the synthesis of these materials.
2. Ethchlorvynol Assay:
In the field of pharmaceuticals, Dichlorodiethylsilane is utilized in the ethchlorvynol assay, which is essential for the analysis and quality control of this specific drug.
3. Organic Synthesis:
Dichlorodiethylsilane serves as a valuable reagent in organic synthesis, where it contributes to the formation of various organic compounds.
4. Pharmaceuticals:
Beyond its use in ethchlorvynol assay, Dichlorodiethylsilane is also employed in the synthesis of other pharmaceutical products, highlighting its versatility in the pharmaceutical industry.
5. Agrochemicals:
In the agrochemical sector, Dichlorodiethylsilane is used as a component in the development of various agrochemical products, such as pesticides and fertilizers.
6. Dyestuffs:
The compound is also utilized in the production of dyes, where its unique properties contribute to the creation of a wide range of colorants for various applications.
Production Methods
Produced by reaction of powdered silicon and ethyl chloride
at 300℃, in the presence of copper powder.
Reactivity Profile
Chlorosilanes, such as Dichlorodiethylsilane, are compounds in which silicon is bonded to from one to four chlorine atoms with other bonds to hydrogen and/or alkyl groups. Chlorosilanes react with water, moist air, or steam to produce heat and toxic, corrosive fumes of hydrogen chloride. They may also produce flammable gaseous H2. They can serve as chlorination agents. Chlorosilanes react vigorously with both organic and inorganic acids and with bases to generate toxic or flammable gases.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Safety Profile
Poison by
intraperitoneal route. Moderately toxic by
ingestion. Corrosive to tissue. Dangerous
fire hazard when exposed to heat, flame, or
oxidzers. Can react vigorously with
oxidizing materials. To fight fire, use foam,
Con, dry chemical. When heated to
decomposition or in reaction with water or
steam it emits toxic and corrosive fumes of
Cl-. See also CHLOROSILANES.
Check Digit Verification of cas no
The CAS Registry Mumber 1719-53-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,1 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1719-53:
(6*1)+(5*7)+(4*1)+(3*9)+(2*5)+(1*3)=85
85 % 10 = 5
So 1719-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H10Cl2Si/c1-3-7(5,6)4-2/h3-4H2,1-2H3
1719-53-5Relevant articles and documents
Design and synthesis of readily degradable acyloxysilane dendrimers
Downing, Christopher M.,Missaghi, Michael N.,Kung, Mayfair C.,Kung, Harold H.
, p. 7502 - 7509 (2011)
Two types of dendrimers with AB2 branching, one with acyloxysilanes at the branching position (V type) and the other at the non-branching position (Y type), were synthesized using hydrosilylation with chlorosilanes followed by heterofunctional condensation with olefin-functional carboxylic acids, and examined as readily degradable template materials. The V type dendrimer was much more susceptible to ligand redistribution with chlorosilanes during preparation, whereas the Y type was less. The acyloxysilane linkages in these dendrimers could be cleaved readily by alcoholysis or hydrolysis on demand, making for suitable templates.
Continuous and batch organomagnesium synthesis of ethyl-substituted silanes from ethylchloride, tetraethoxysilane, and organotrichlorosilane for production of polyethylsiloxane liquids. 2. Continuous one-step synthesis of ethylethoxy- and ethylchlorosilanes
Klokov, Boris A.
, p. 234 - 240 (2001)
Development of a continuous one-step manufacturing process for ethylethoxy- and ethylchlorosilanes is described. The methodology of synthesis of ethyl-substituted silanes has been improved. The important factors for the successful synthesis have been determined. Among them are (1) the replacement of some tetraethoxysilane 3 by ethyltrichlorosilane 10, (2) the optimum concentration of 3 and 10, (3) the excess of the granulated magnesium (the supply rate 50-110 g h-1), and, finally, (4) the columnar apparatus with the stirrer, resulting in high yields of di-and triethylsilanes, low duration of synthesis, and high selectivity of Grignard reagent. Continuous one-step synthesis has been assimilated into industry (up to a scale 7-40 kg h-1 of magnesium) for production of oligoethylsiloxanes with low (5-20%) and high content (up to 40%) of the terminal triethylsiloxy groups. The rules for R/D process of the Grignard synthesis are described.
-
Sommer, L. H.,Bailey, D. L.,Whitmore, F. C.
, p. 2869 - 2872 (1948)
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Neutral-Eosin-Y-Photocatalyzed Silane Chlorination Using Dichloromethane
Fan, Xuanzi,Xiao, Pin,Jiao, Zeqing,Yang, Tingting,Dai, Xiaojuan,Xu, Wengang,Tan, Jin Da,Cui, Ganglong,Su, Hongmei,Fang, Weihai,Wu, Jie
supporting information, p. 12580 - 12584 (2019/08/16)
Chlorosilanes are versatile reagents in organic synthesis and material science. A mild pathway is now reported for the quantitative conversion of hydrosilanes to silyl chlorides under visible-light irradiation using neutral eosin Y as a hydrogen-atom-transfer photocatalyst and dichloromethane as a chlorinating agent. Stepwise chlorination of di- and trihydrosilanes was achieved in a highly selective fashion assisted by continuous-flow micro-tubing reactors. The ability to access silyl radicals using photocatalytic Si?H activation promoted by eosin Y offers new perspectives for the synthesis of valuable silicon reagents in a convenient and green manner.
A direct method for preparing ethyldichlorosilane and its comparison with known alternative methods
Lebedev,Sheludyakov,Lebedeva,Ovcharuk,Govorov,Kalinina
, p. 629 - 633 (2014/11/08)
Various methods, alternative to direct synthesis, for preparing an important commercial organosilicon monomer, ethyldichlorosilane, were studied in detail. The methods, including organomagnesium and organoaluminum procedures, hydrosilylation, and combined methods, were analyzed from the viewpoint of feasibility of laboratory and small-tonnage commercial production, and their advantages and drawbacks were revealed.