17200-29-2Relevant articles and documents
An efficient synthesis of benzoxazoles using silica-supported tin exchanged silicotungstic acid catalyst
Srivani,Venkateswar Rao,Sai Prasad,Lingaiah
, p. 119 - 123 (2010)
An efficient method for the preparation of benzoxazoles by reacting aminophenols with orthoesters in the presence of silica-supported tin exchanged silicotungstic acid catalyst under mild conditions with high yield and selectivity is demonstrated. The catalysts were characterized by FT-IR and pyridine adsorbed FT-IR. The catalyst exhibited consistent activity upon recycling and is highly active compared to other catalysts. The role of Lewis acidity of the catalysts and plausible reaction mechanism is presented.
Room-temperature palladium-catalyzed direct 2-alkenylation of azole derivatives with alkenyl bromides
Yao, Yun-Xin,Fang, Dong-Mei,Gao, Feng,Liang, Xiao-Xia
supporting information, p. 68 - 71 (2018/12/05)
Pd-catalyzed direct C2-alkenylation of azole derivatives proceeds efficiently under mild conditions, and the reaction of substituted benzoxazoles, oxazole and benzothiazole occurred even at room temperature. The substrate scope of the reaction was turned out to include mono-, di- and trisubstituted alkenyl bromides. To validate the scalability of this method, 5-Methyl-2-(prop-1-en-2-yl)benzoxazole (3c) was prepared on one-gram scale at room temperature.
Method for synthesizing benzoxazole through microwave radiation of benzamide compound in water phase
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Paragraph 0072, (2019/03/08)
The invention discloses a method for synthesizing benzoxazole through microwave radiation of a benzamide compound in a water phase. The benzamide compound is added into the water phase under the microwave condition to be subjected to a cyclization reaction for generating the benzoxazole under the alkali condition, and the method for preparing the benzoxazole is environmentally friendly, easy and convenient to operate, safe, low in cost and efficient. Compared with the prior art, the method can be applied to a large number of functional groups, the yield is high, the number of by-products is small, and the method is easy to operate, safe, low in cost and environmentally friendly. (Please see the specifications for the formula).