17613-40-0

Basic information

• Product Name: 6-Bromophenanthridine
• Synonyms: 6-Bromophenanthridine
• CAS NO: 17613-40-0
• Molecular Formula: C₁₃H₈BrN
• Molecular Weight: 258.11332
• Mol File: 17613-40-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 118-120 °C(Solv: methanol (67-56-1))
• Boiling Point: 399.808°C at 760 mmHg
• Flash Point: 195.597°C
• Appearance: /
• Density: 1.544
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.745
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 2.28±0.40(Predicted)
• CAS DataBase Reference: 6-Bromophenanthridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromophenanthridine(17613-40-0)
• EPA Substance Registry System: 6-Bromophenanthridine(17613-40-0)

Safety Data

• Hazardous Substances Data: 17613-40-0(Hazardous Substances Data)

Usage

General Description

6-Bromophenanthridine is a chemical compound with the molecular formula C18H13BrN. It belongs to the class of phenanthridine alkaloids and is derived from plants like Thalictrum minus and Thalictrum flavum. It is known for its potential therapeutic properties, including anti-cancer, anti-inflammatory, and antifungal activities. Studies have shown that 6-Bromophenanthridine exhibits cytotoxic effects against various cancer cell lines and has the potential to be used in the development of new anti-cancer drugs. Additionally, it has demonstrated anti-inflammatory effects by inhibiting the production of inflammatory mediators. Furthermore, its antifungal properties make it a promising candidate for the development of novel antifungal agents. Overall, 6-Bromophenanthridine is a valuable compound with potential applications in the fields of medicine and pharmaceuticals.

InChI:InChI=1/C13H8BrN/c14-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)15-13/h1-8H

Upstream product

• 41001-33-6 2-chlorophenanthridine 
• 90-41-5 2-phenylaniline 
• 23088-28-0 N-([1,1'-biphenyl]-2-yl)-2-chloroacetamide 
• 40484-36-4 6-(chloromethyl)phenanthridine 
• 3128-77-6 2-isocyanobiphenyl 
• 173379-08-3 1,1'-biphenyl-2-yl isocyanide dibromide 
• 1015-89-0 6(5H)-phenanthridinone 

Downstream Products

• 3340-87-2 6-phenoxyphenanthridine 
• 229-87-8 phenanthridine 

Relevant articles and documents

Asymmetric Synthesis of Heterocyclic Chloroamines and Aziridines by Enantioselective Protonation of Catalytically Generated Enamines**

We report a method for the synthesis of chiral vicinal chloroamines via asymmetric protonation of catalytically generated prochiral chloroenamines using chiral Br?nsted acids. The process is highly enantioselective, with the origin of asymmetry and catalyst substituent effects elucidated by DFT calculations. We show the utility of the method as an approach to the synthesis of a broad range of heterocycle-substituted aziridines by treatment of the chloroamines with base in a one-pot process, as well as the utility of the process to allow access to vicinal diamines.

SYNTHESE DANS LA SERIE DES PHENANTHRIDINES. IV. PREPARATION DE NOUVEAUX RADIOPROTECTEURS A MOTIF PHENANTHRIDINE

New phenanthridines substituted in the 6-position by a β-aminoethylthiol chain have been synthesized.These new products are easily obtained from 6-methylphenanthridine by a Mannich reaction or from 6-bromophenanthridine by substitution.From the 6-carboxaldehydophenanthridine and the β-aminoethylthiol, the corresponding thiazolidine or imine are obtained.These compounds are likely to be new radioprotectors.