176483-80-0

Basic information

• Product Name: 1H-1,4,7-Triazonine, octahydro-1,4-bis(1-methylethyl)-7-[(4-methylphenyl)sulfonyl]-
• CAS NO: 176483-80-0
• Molecular Formula: C19H33N3O2S
• Molecular Weight: 367.556
• Mol File: 176483-80-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-1,4,7-Triazonine, octahydro-1,4-bis(1-methylethyl)-7-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,4,7-Triazonine, octahydro-1,4-bis(1-methylethyl)-7-[(4-methylphenyl)sulfonyl]-(176483-80-0)
• EPA Substance Registry System: 1H-1,4,7-Triazonine, octahydro-1,4-bis(1-methylethyl)-7-[(4-methylphenyl)sulfonyl]-(176483-80-0)

Safety Data

• Hazardous Substances Data: 176483-80-0(Hazardous Substances Data)

Usage

Molar mass

385.575 g/mol

Structure

Triazonine ring with a sulfonyl group attached to the seventh carbon atom

Isopropyl groups

Two

Methylphenyl group

One

Physical and chemical properties

Unique due to the presence of isopropyl and methylphenyl groups

Potential applications

Pharmaceutical or chemical industries (further research needed)

Upstream product

• 52667-89-7 N,N',N-tris(p-toluenesulfonyl)-1,4,7-triazacyclononane 
• 98-59-9 p-toluenesulfonyl chloride 
• 56187-04-3 1,4,7-tritosyl-1,4,7-triazaheptane 
• 129422-96-4 1-(p-toluenesulfonyl)-1,4,7-triazacyclononane 
• 75-26-3 isopropyl bromide 

Relevant articles and documents

DNA hydrolysis catalyzed by tris(diisopropyl-1,4,7-triazacyclononanes) ethane metal complexes

Novel trinuclear coordinated ligands were designed using three of 1,4,7-triazacyclononane moieties with a tribromo linker. These ligands show greater capability and potency in association with various metal ions. Tris(diisopropyl-1,4,7-triazacyclononanes)ethane (2) associated with Cu 2+ and Ce4+ ions shows better reactivity to achieve DNA hydrolysis at 37 °C at pH 8 for 5 hr. Using high resolution of polyacrylamide gel electrophoresis, DNA cleavage reaction in Tris-HCl buffer causes a nicking site at the single-stranded region. Alternatively, the reaction in HEPES buffer shows a random DNA cleavage included the double-stranded region. Hydrolysis of phosphodiester bond mediated by trinuclear metal complex is capable of performing at the physiological temperature 37 °C, but it has a lower reactivity compared to mono- and di-nuclear metal complexes. The result suggests that trinuclear metal complexes have a bulky environment to prevent from going toward the phosphodiester bond. The design of an efficient chemical hydrolyase will be a challenge in order to construct a coordinate ligand with the enhancement of hydrolytic activity and the reduction of the steric environment.

Structural characterization of the first example of a bis(μ-thiolato)dicopper(II) complex. Relevance to proposals for the electron transfer sites in cytochrome c oxidase and nitrous oxide reductase

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