17961-78-3

Basic information

• Product Name: Silane, trimethyl(1-phenylethyl)-
• Synonyms: 1-phenyl-1-trimethylsilylethane;1-Phenyl-1-trimethylsilylethan
• CAS NO: 17961-78-3
• Molecular Formula: C11H18Si
• Molecular Weight: 178.349
• Mol File: 17961-78-3.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Silane, trimethyl(1-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, trimethyl(1-phenylethyl)-(17961-78-3)
• EPA Substance Registry System: Silane, trimethyl(1-phenylethyl)-(17961-78-3)

Safety Data

• Hazardous Substances Data: 17961-78-3(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 7282-39-5 (1-phenyl-ethyl)methyldichlorosilane 
• 75-16-1 methylmagnesium bromide 
• 75-77-4 chloro-trimethyl-silane 
• 98-85-1 1-Phenylethanol 
• 672-65-1 (1-chloroethyl)benzene 
• 14856-75-8 1-phenyl-1-trimethylsilyloxyethane 
• 7100-97-2 1-fluoro-1-phenylethane 
• 14296-15-2 (RS)-α-methylbenzenemethyl 2,2-dimethylpropanoate 
• 4013-34-7 3-phenyl-2-oxabutane 
• 38053-74-6 (1-phenylethyl)trichlorosilane 
• 676-58-4 methylmagnesium chloride 
• 993-07-7 trimethylsilan 
• 585-71-7 (1-bromoethyl)benzne 

Downstream Products

• 89103-72-0 (1S,2S)-1,2-diphenylpropan-1-ol 
• 7693-84-7 (1S,2R)-1,2-diphenylpropan-1-ol 
• 1502-73-4 erythro-2-Phenyl-4,4-dimethyl-3-pentanol 
• 738617-33-9 (3S,4S)-2,2-dimethyl-4-phenyl-3-pentanol 
• 19263-14-0 3-Phenyl-1,2-butanedicarboxylic acid 
• 3279-79-6 8-Isopropyl-coffein 
• 81290-09-7 2-trimethylsilyl-1,2-diphenylpropane 
• 136289-31-1 1,4-dicyano-1-(α-methylbenzyl)naphthalene 
• 139097-57-7 4-cyano-1-(α-methylbenzyl)-naphthalene 
• 136289-31-1 1,4-dicyano-1-(α-methylbenzyl)naphthalene 
• 71435-96-6 <(1.4-Cyclohexadien-1-yl)ethyl>trimethylsilan 

Relevant articles and documents

Nickel-Mediated Enantiospecific Silylation via Benzylic C-OMe Bond Cleavage

Benzylic stereocenters are found in bioactive and drug molecules, as enantiopure benzylic alcohols have been used to build such a stereogenic center, but are limited to the construction of a C-C bond. Silylation of alkyl alcohols has the potential to build bioactive molecules and building blocks; however, the development of such a process is challenging and unknown. Herein, we describe an unprecedented AgF-assisted nickel catalysis in the enantiospecific silylation of benzylic ethers.

Fluoroalkylselenolation of Alkyl Silanes/Trifluoroborates under Metal-Free Visible-Light Photoredox Catalysis

Herein a metal-free fluoroalkylselenolation of alkylsilanes as well as potassium alkyltrifluoroborates under visible light photocatalysis is disclosed. The developed methodologies are performed under mild conditions, room temperature in the presence of an organic photocatalyst and blue LED irradiation. Mechanistic investigations including luminescence and EPR spectroscopy allow us to shed light on both mechanisms.

Hydrosilane synthesis via catalytic hydrogenolysis of halosilanes using a metal-ligand bifunctional iridium catalyst

Hydrogenolysis of various halosilanes was catalysed by iridium amido complexes to produce hydrosilanes. Selective monohydrogenolysis of di- and trichlorosilanes similarly proceeded, resulting in the formation of chlorohydrosilanes (R2SiHCl or RSiHCl2) as synthetically important building blocks for various organosilicon compounds. A mechanistic study supported the in-situ formation of an iridium hydride species as a key intermediate, which could transfer the hydride to the silicon atom through a metal–ligand bifunctional mechanism. One-pot hydrotrimethylsilylation of olefins was achieved via successive hydrogenolysis and hydrosilylation reactions starting from Me3SiCl.