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184586-12-7

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184586-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 184586-12-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,5,8 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 184586-12:
(8*1)+(7*8)+(6*4)+(5*5)+(4*8)+(3*6)+(2*1)+(1*2)=167
167 % 10 = 7
So 184586-12-7 is a valid CAS Registry Number.

184586-12-7Downstream Products

184586-12-7Relevant articles and documents

New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals. Part 2

Ishiyama, Takashi,Iimura, Shin,Yoshino, Toshiharu,Chiba, Jun,Uoto, Kouichi,Terasawa, Hirofumi,Soga, Tsunehiko

, p. 2815 - 2819 (2007/10/03)

To investigate structure-activity relationships of the 9,10-acetal-9β-dihydro taxoids, we modified the 7-hydroxyl groups of the 9,10-acetonide-3′-(4-pyridyl) analogue to deoxy, methoxy, α-F, and 7β,8β-methano group. As a result of this study, we found that the 7-deoxy analogue was the strongest among these analogues. In addition, we found that the 7-deoxy-3′-(4-pyridyl) and 7-deoxy-3′-(2-pyridyl) analogues showed stronger activity against cell lines expressing P-glycoprotein than the corresponding 3′-phenyl analogue.

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