1921-90-0 Usage
Description
(E)-2-benzylidenecyclopentanone, with the molecular formula C11H12O, is a yellow crystalline solid that serves as a crucial building block in the synthesis of various organic compounds. It is renowned for its versatile reactivity and is extensively utilized in the production of pharmaceuticals, fragrances, and other fine chemicals. Its unique structure and properties make it a valuable asset in organic synthesis, and it is widely used in both research and industrial applications. Furthermore, (E)-2-benzylidenecyclopentanone has demonstrated biological activity, suggesting potential therapeutic benefits in the medical field. Overall, this chemical compound holds a significant role in the realms of chemistry and pharmaceutical science due to its diverse applications and potential benefits.
Uses
Used in Pharmaceutical Industry:
(E)-2-benzylidenecyclopentanone is used as a key intermediate for the synthesis of various pharmaceuticals. Its versatile reactivity allows for the creation of a wide range of medicinal compounds, contributing to the development of new drugs and therapies.
Used in Fragrance Industry:
In the fragrance industry, (E)-2-benzylidenecyclopentanone is used as a building block for the creation of various scent compounds. Its unique structure enables the development of novel and complex fragrances, enhancing the industry's ability to innovate and diversify its product offerings.
Used in Fine Chemicals Industry:
(E)-2-benzylidenecyclopentanone is also utilized in the production of fine chemicals, which are high-purity chemicals used in various applications, including research, specialty manufacturing, and the development of advanced materials. Its role in this industry highlights its versatility and the breadth of its applications.
Used in Research and Development:
(E)-2-benzylidenecyclopentanone is employed as a valuable building block in research and development, where its unique structure and properties are harnessed to explore new chemical reactions and synthesize novel compounds. This contributes to the advancement of scientific knowledge and the discovery of new materials and applications.
Used in Organic Synthesis:
As a key component in organic synthesis, (E)-2-benzylidenecyclopentanone is used to create a diverse array of organic compounds. Its reactivity and structural properties make it an essential tool in the development of new chemical products and materials.
Potential Therapeutic Applications:
(E)-2-benzylidenecyclopentanone has shown biological activity, suggesting that it may have potential therapeutic benefits in medicine. Further research and development in this area could lead to the discovery of new treatments and therapies for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1921-90-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,2 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1921-90:
(6*1)+(5*9)+(4*2)+(3*1)+(2*9)+(1*0)=80
80 % 10 = 0
So 1921-90-0 is a valid CAS Registry Number.
1921-90-0Relevant articles and documents
Synthesis of unsymmetrical dienones with heteroaromatic substituents
Vatsadze,Sviridenkova,Manaenkova,Semashko,Zyk
, p. 2224 - 2225 (2005)
Condensation of heteroaromatic aldehydes with 2-benzylidenecyclopentanone in a basic medium afforded a number of unsymmetrical 2,5- diarylidenecyclopentanones. According to 1H NMR data, the dienones obtained were the E,E-isomers.
Design and Green Synthesis of Piperlongumine Analogs and Their Antioxidant Activity against Cerebral Ischemia-Reperfusion Injury
Li, Ge,Zheng, Yuantie,Yao, Jiali,Hu, Linya,Liu, Qunpeng,Ke, Furong,Feng, Weixiao,Zhao, Ya,Yan, Pencheng,He, Wenfei,Deng, Hui,Qiu, Peihong,Li, Wulan,Wu, Jianzhang
, p. 4545 - 4557 (2019)
The supplementation of exogenous antioxidants to scavenge excessive reactive oxygen species (ROS) is an effective treatment for cerebral ischemia-reperfusion injury (CIRI) in stroke. Piperlongumine (PL), a natural alkaloid, has a great potential as a neur
Ruthenium-catalysed synthesis of chiral exocyclic allylic alcoholsviachemoselective transfer hydrogenation of 2-arylidene cycloalkanones
Zhang, Kaili,Liu, Qixing,He, Renke,Chen, Danyi,Deng, Zhangshuang,Huang, Nianyu,Zhou, Haifeng
supporting information, p. 1628 - 1632 (2021/03/09)
An exclusive asymmetric reduction of C=O bonds of 2-arylidene four-, five-, six-, and seven-membered cycloalkanones has been studied systematically. The asymmetric transfer hydrogenation was performed using a robust and commercially available chiral diamine-derived ruthenium complex as a catalyst and HCOOH/Et3N as a hydrogen source under mild conditions, giving 51 examples of chiral exocyclic allylic alcohols in up to 96% yield and 99% ee. This method was also applicable to the gram-scale synthesis of the active intermediates of the anti-inflammatory loxoprofen and natural product (?)-goniomitine.
Metal- and Solvent-Free Transesterification and Aldol Condensation Reactions by a Homogenous Recyclable Basic Ionic Liquid Based on the 1,3,5-Triazine Framework
Hu, Yanqiu,Kazemnejadi, Milad,Ren, Mingqi
, p. 775 - 783 (2021/08/30)
A new recyclable basic ionic liquid was introduced as an efficient catalyst for aldol condensation and transesterification reactions under environmentally friendly conditions. The catalyst was prepared based on methyl imidazolium moieties bearing hydroxide counter anions via the Hofmann elimination on a 1,3,5-triazine framework. The ionic liquid with two functionalities including anion stabilizer and high basicity, was used as an efficient catalyst for aldol condensation as well as transesterification reaction of a variety of alkyl benzoates. All reactions were performed in the absence of any external reagent, co-catalyst, or solvent, in line with environmental protection. The kinetics isotope effect (KIE) was conducted for the transesterification reaction to elucidate the mechanism and rate determining step (RDS). It worth noted that, the homogeneous catalyst could be recycled from the reaction mixture and reused for several consecutive runs with insignificant drop of basicity and conversion.
