199277-80-0Relevant articles and documents
Cobalt-Catalyzed Asymmetric Hydrogenation of Vinylsilanes with a Phosphine-Pyridine-Oxazoline Ligand: Synthesis of Optically Active Organosilanes and Silacycles
Zuo, Ziqing,Xu, Songgen,Zhang, Lei,Gan, Lan,Fang, Huaquan,Liu, Guixia,Huang, Zheng
, p. 3906 - 3911 (2019)
The asymmetric hydrogenation of vinylsilanes catalyzed by a new C1-symmetric phosphine-pyridine-oxazoline cobalt complex is described. The method provides an efficient approach to chiral tertiary silanes with enantioselectivities up to 99% ee.
Enantioselective Synthesis of N-Benzylic Heterocycles: A Nickel and Photoredox Dual Catalysis Approach
Pezzetta, Cristofer,Bonifazi, Davide,Davidson, Robert W. M.
, p. 8957 - 8961 (2019/11/11)
Reported herein is a dual nickel- and photoredox-catalyzed modular approach for the preparation of enantioenriched N-benzylic heterocycles. α-Heterocyclic carboxylic acids, easily obtainable from common commercial material, are reported as suitable substrates for a decarboxylative strategy in conjunction with a chiral pyridine-oxazoline (PyOx) ligand, providing quick access to enantioenriched drug-like products. The presence of a directing group on the heterocyclic moiety is shown to be beneficial, affording improved stereoselectivity in a number of cases.
Chiral oxazolinylpyridines as ligands for enantioselective palladium catalysed allylic substitution
Chelucci, Giorgio,Medici, Serenella,Saba, Antonio
, p. 3183 - 3184 (2007/10/03)
Chiral oxazolinylpyridines were prepared and assessed in the enantioselective palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimethyl malonate. Enantioselectivity up to 91% was obtained.