20200-22-0

Basic information

• Product Name: N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE
• Synonyms: N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE;BUTTPARK 45\09-97;N-Methyl-2-nitro-4-(trifluoromethyl);N-Methyl-2-nitro-4-(trifluoromethyl)benzenamine;N-Methyl-N-[2-nitro-4-(trifluoromethyl)-phenyl]amine;4-(Methylamino)-3-nitrobenzotrifluoride;N-Methyl-2-nitro-4-(trifluoromethyl)aniline, N-Methyl-2-nitro-alpha,alpha,alpha-trifluoro-p-toluidine
• CAS NO: 20200-22-0
• Molecular Formula: C₈H₇F₃N₂O₂
• Molecular Weight: 220.15
• EINECS: 243-586-5
• Product Categories: Amines;blocks;FluoroCompounds;NitroCompounds
• Mol File: 20200-22-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 73-75 °C(Solv: ethanol (64-17-5))
• Boiling Point: 262.1 °C at 760 mmHg
• Flash Point: 112.3 °C
• Appearance: /
• Density: 1.427 g/cm³
• Vapor Pressure: 0.0111mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -3.14±0.25(Predicted)
• CAS DataBase Reference: N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE(20200-22-0)
• EPA Substance Registry System: N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE(20200-22-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 20200-22-0(Hazardous Substances Data)

Usage

Uses

N-Methyl-2-nitro-4-trifluoromethylaniline

InChI:InChI=1/C8H7F3N2O2/c1-12-6-3-2-5(8(9,10)11)4-7(6)13(14)15/h2-4,12H,1H3

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 74-89-5 methylamine 
• 367-86-2 1-fluoro-2-nitro-4-trifluoromethyl-benzene 
• 300698-92-4 N-methyl-N-[2-nitro-4-(trifluoromethyl)phenyl]acetamide 
• 396-12-3 N-[2-nitro-4-(trifluoromethyl)phenyl]acetamide 
• 400-98-6 4-trifluoromethyl-2-nitroaniline 
• 74-88-4 methyl iodide 
• 593-51-1 methylamine hydrochloride 
• 109-83-1 (2-hydroxyethyl)(methyl)amine 

Downstream Products

• 690231-99-3 4-chloro-3-(1-methyl-5-trifluoromethyl-1H-benzoimidazol-2-yl)-phenylamine 
• 690231-96-0 2-(2-chloro-5-nitro-phenyl)-1-methyl-5-trifluoromethyl-1H-benzoimidazole 
• 690231-92-6 2-chloro-N-(2-methylamino-5-trifluoromethyl-phenyl)-5-nitro-benzamide 
• 1267635-07-3 C₂₁H₂₀F₃N₃O₃ 
• 1267635-51-7 C₂₃H₁₇F₃N₂O₂ 
• 1267635-54-0 C₁₇H₁₃F₃N₂O₂ 
• 22365-40-8 triflubazam 
• 37957-76-9 3-dimethylaminomethylene-1-methyl-5-phenyl-7-trifluoromethyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione 
• 64910-45-8 4-(methylamino)-3-nitrobenzonitrile 
• 53483-66-2 1-methyl-5-(trifluoromethyl)-1H-benzo[d]imidazole 
• 859877-15-9 3-bromo-N²-methyl-5-trifluoromethyl-benzene-1,2-diamine 
• 859877-14-8 (2-bromo-6-nitro-4-trifluoromethyl-phenyl)-methyl-amine 
• 35203-49-7 N¹-methyl-4-(trifluoromethyl)benzene-1,2-diamine 

Relevant articles and documents

Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes

CuH-catalyzed intramolecular cyclization and intermolecular allylation of benzimidazoles with allenes have been described. The reaction proceeded smoothly with the catalytic system of Cu(OAc)2/Xantphos and catalytic amount of (MeO)2MeSiH. This protocol features mild reaction conditions and a good tolerance of substrates bearing electron-withdrawing, electron-donating, or electron-neutral groups. A new catalytic mechanism was proposed for this copper hydride catalytic system.

2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS

The present invention provides compounds that are useful as vaccine adjuvants and/or antitumor agents and methods for producing and using the same. In one particular aspect of the invention, compounds of the invention are of the formula (I) where R1, R2, R3 and Ar1 are those defined herein.

FUSED HETEROCYCLIC COMPOUND AND USE THEREOF

A fused heterocyclic compound of formula (1): wherein, A1 and A2 represent a nitrogen atom or the like, R1, R2, R3 and R4 represent a halogen atom or the like, R2 and R3 represent a halogen atom or the like, R5 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, or the like, R6 and R7 represent a C1-C4 chain hydrocarbon group substituted with one or more halogen atoms, or the like, and n represents 0 or 1, has an excellent noxious arthropod controlling effect.