204452-93-7

Basic information

• Product Name: 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde
• Synonyms: 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde;5,6,7,8-Tetrahydro-1,8-naphthyridine-2-carboxaldehyde;1,5,6,7-tetrahydro-1,8-naphthyridine-2-carbaldehyde
• CAS NO: 204452-93-7
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.191
• Mol File: 204452-93-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63.5-64 °C
• Boiling Point: 326.091°C at 760 mmHg
• Flash Point: 151.015°C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.595
• PKA: 10.31±0.40(Predicted)
• CAS DataBase Reference: 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde(204452-93-7)
• EPA Substance Registry System: 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde(204452-93-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 204452-93-7(Hazardous Substances Data)

Usage

General Description

5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde is a chemical compound with the molecular formula C11H11NO. It is a heterocyclic aldehyde that belongs to the class of naphthyridine compounds. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also known for its potential biological activities, such as antibacterial and antifungal properties. Additionally, 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carbaldehyde has been studied for its potential applications in the development of new drugs and as a precursor for the synthesis of other valuable compounds.

InChI:InChI=1/C9H10N2O/c12-6-8-4-3-7-2-1-5-10-9(7)11-8/h3-4,6H,1-2,5H2,(H,10,11)

Upstream product

• 204452-90-4 2-(dimethoxymethyl)-1,8-naphthyridine 
• 7521-41-7 2-Aminonicotinaldehyde 
• 204452-91-5 3(S)-(6-methoxypyridin-3-yl)-3-alanine tert-butyl ester p-toluenesulfonic acid 

Downstream Products

• 227963-15-7 (S)-3-(6-methoxypyridin-3-yl)-3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoic acid 
• 206989-41-5 3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propane-1-amine 
• 381678-78-0 (5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)methanol 

Relevant articles and documents

COMPOSITION AND METHODS FOR TREATING CHRONIC KIDNEY DISEASE

This invention relates to the treatment of chronic kidney disease, including diabetic nephropathy, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, non-diabetic chronic kidney disease, renal fibrosis or acute kidney injury by the administrat

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The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.

An efficient synthesis of an alphavbeta3 antagonist.

A practical preparation of an alpha(v)beta(3) antagonist is reported. The antagonist consists of three key components, a tetrahydronaphthyridine moiety, a beta-alanine moiety, and a central imidazolidone moiety. The tetrahydronaphthyridine component was p