20849-82-5

Basic information

• Product Name: 3-(4-METHOXYPHENYL)-2-METHYL-1-PROPENE
• Synonyms: 3-(4-METHOXYPHENYL)-2-METHYL-1-PROPENE
• CAS NO: 20849-82-5
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.23
• Mol File: 20849-82-5.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 229.9°C at 760 mmHg
• Flash Point: 84.9°C
• Appearance: /
• Density: 0.931g/cm³
• Vapor Pressure: 0.102mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 3-(4-METHOXYPHENYL)-2-METHYL-1-PROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXYPHENYL)-2-METHYL-1-PROPENE(20849-82-5)
• EPA Substance Registry System: 3-(4-METHOXYPHENYL)-2-METHYL-1-PROPENE(20849-82-5)

Safety Data

• Hazardous Substances Data: 20849-82-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O/c1-9(2)8-10-4-6-11(12-3)7-5-10/h4-7H,1,8H2,2-3H3

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 563-47-3 3-Chloro-2-methylpropene 
• 75-09-2 dichloromethane 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 1333226-27-9 C₁₈H₂₁NO₄S₂ 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 877-99-6 1-methoxy-4-(2-methyl-1-propenyl)benzene 
• 820-71-3 methallyl acetate 
• 14568-34-4 2-methylprop-2-ene-1-sulfonyl chloride 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 64506-21-4 (+/-)-2-methyl-3-(p-methoxyphenyl)propanol 
• 1239669-02-3 C₂₀H₂₃NO₅S 
• 1239669-04-5 C₂₀H₂₃NO₅S 
• 877-99-6 1-methoxy-4-(2-methyl-1-propenyl)benzene 

Relevant articles and documents

Microwave-assisted palladium-catalyzed allylation of aryl halides with homoallyl alcohols via retro-allylation

The palladium-catalyzed allylation of aryl halides with homoallyl alcohols via retro-allylation proceeds at 200-250 °C in a toluene-DMF mixed solvent using microwave heating. Even at such high temperatures, the regio- and stereospecificity of the allyl tr

Original antileishmanial hits: Variations around amidoximes

In continuation to our previous findings on amidoximes' antiparasitic activities, a new series of 23 original derivatives was designed and obtained by convergent synthesis. First, new terminal alkenes were synthesized by cross-coupling reaction. Then, cyclization was performed between terminal alkenes and β-ketosulfones using manganese(III) acetate reactivity. Twenty-three amidoximes were tested for their in vitro activity against Leishmania amazonensis promastigotes and their toxicity on murine macrophages. Seven of the tested compounds exhibited an antileishmanial activity at lower than 10 μM with moderate to low toxicity. Six of these molecules showed activity at lower than 10 μM against promastigotes and toxicity at higher than 50 μM were selected and evaluated for their activity against intracellular Leishmania amazonensis amastigotes. Modulating chemical substituents in position 2 of dihydrofuran highly influenced their antileishmanial activities. The introduction of a methyl or trifluoromethyl group on the benzene ring of the benzyl group had a positive influence on activity without significantly increasing toxicity (52, 59, 60).

Trifluoromethylchlorosulfonylation of alkenes: Evidence for an inner-sphere mechanism by a copper phenanthroline photoredox catalyst

Abstract A visible-light-mediated procedure for the unprecedented trifluoromethylchlorosulfonylation of unactivated alkenes is presented. It uses [Cu(dap)2]Cl as catalyst, and contrasts with [Ru(bpy)3]Cl2, [Ir(ppy)2(dtbbpy)]PF6, or eosin Y that exclusively give rise to trifluoromethylchlorination of the same alkenes. It is assumed that [Cu(dap)2]Cl plays a dual role, that is, acting both as an electron transfer reagent as well as coordinating the reactants in the bond forming processes. Double role: The trifluoromethylchlorosulfonylation of unactivated alkenes was developed using [Cu(dap)2]Cl as catalyst (dap=2,9-bis(para-anisyl)-1,10-phenanthroline). [Cu(dap)2]Cl plays a dual role; acting as an electron transfer reagent as well as coordinating the reactants in the bond forming processes.