2114-29-6

Basic information

• Product Name: 1-phenylpropyl acetate
• Synonyms: 1-phenylpropyl acetate;ETHYLPHENYLCARBINYLACETATE;1-Phenylpropylacetat;alpha-ethyl-benzenemethano acetate;Benzenemethanol, .alpha.-Ethyl-, acetate;Acetic acid 1-phenylpropyl ester;α-Ethylbenzenemethanol acetate;α-Ethylbenzyl acetate
• CAS NO: 2114-29-6
• Molecular Formula: C11H14O2
• Molecular Weight: 178.22766
• EINECS: 218-312-2
• Mol File: 2114-29-6.mol
• Article Data: 116

Chemical Properties

• Boiling Point: 229.5°Cat760mmHg
• Flash Point: 91.7°C
• Appearance: /
• Density: 1.012g/cm³
• Vapor Pressure: 0.0693mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 1-phenylpropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylpropyl acetate(2114-29-6)
• EPA Substance Registry System: 1-phenylpropyl acetate(2114-29-6)

Safety Data

• Hazardous Substances Data: 2114-29-6(Hazardous Substances Data)

Usage

Description

1-Phenylpropyl acetate, also known as alpha-Phenylpropyl acetate, is a chemical compound with the formula C11H14O2. It is an ester characterized by a sweet, floral odor and is commonly used as a fragrance ingredient in perfumes and other cosmetic products. It is also found in various fruits, such as apple and strawberry, contributing to their aroma.

Uses

Used in Flavor and Fragrance Industry:
1-Phenylpropyl acetate is used as a fragrance ingredient for its pleasant and long-lasting scent, enhancing the overall aroma of perfumes and cosmetic products.
Used in Food Industry:
1-Phenylpropyl acetate is used as a flavoring agent in food products, providing a sweet and fruity note to enhance the overall taste.

InChI:InChI=1/C11H14O2/c1-3-11(13-9(2)12)10-7-5-4-6-8-10/h4-8,11H,3H2,1-2H3

Upstream product

• 93-54-9 1-Phenyl-1-propanol 
• 108-24-7 acetic anhydride 
• 103-65-1 phenylpropane 
• 546-67-8 lead(IV) tetraacetate 
• 64-19-7 acetic acid 
• 873-66-5 1-propenylbenzene 
• 766-90-5 cis-1-phenyl-1-propylene 
• 100-42-5 styrene 
• 17279-31-1 (-)-(S)-N,N-dimethyl-1-phenylethylamine 
• 108-22-5 Isopropenyl acetate 
• 108-05-4 vinyl acetate 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 2082-59-9 pentanoic anhydride 
• 106-31-0 butanoic acid anhydride 

Downstream Products

• 1565-74-8 (R)-1-phenyl-1-propanol 
• 613-87-6 (S)-1-phenyl-1-propanol 
• 2114-29-6 (R)-1-phenylpropyl acetate 
• 2114-29-6 (S)-1-phenylpropyl acetate 
• 93-54-9 1-Phenyl-1-propanol 
• 34835-98-8 1-phenyl-1-p-tolyl-propane 
• 1391941-05-1 1-methyl-2-(1-phenylpropyl)benzene 
• 10340-48-4 hex-5-en-3-ylbenzene 
• 7642-42-4 (E)-1-phenylprop-1-en-1-yl acetate 

Relevant articles and documents

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Rh-catalyzed asymmetric hydrogenation of α-aryl-β-alkylvinyl esters with chiral ferrocenylphosphine-phosphoramidite ligand

An enantioselective Rh-catalyzed hydrogenation of E/Z mixtures of trisubstituted vinyl esters has been disclosed. With a combination of [Rh(COD)2]BF4 and a structurally fine-tuning chiral ferrocenylphosphine-phosphoramidite ligand as the catalyst, a variety of E/Z mixtures of α-aryl-β-alkylvinyl esters have been successfully hydrogenated in high yields and with good to high enantioselectivities (up to 96% ee). The presence of a small amount of tBuOH proved to be beneficial to improve the hydrogenation outcome.

Evaluation of gem-Diacetates as Alternative Reagents for Enzymatic Regio-and Stereoselective Acylation of Alcohols

Geminal diacetates have been used as sustainable acyl donors for enzymatic acylation of chiral and nonchiral alcohols. Especially, it was revealed that geminal diacetates showed higher reactivity than vinyl acetate for hydrolases that are sensitive to acetaldehyde. Under optimized conditions for enzymatic acylation, several synthetically relevant saturated and unsaturated acetates of various primary alcohols were obtained in very high yields up to 98% without E/Z isomerization of the double bond. Subsequently, the acyl donor was recreated from the resulting aldehyde and reused constantly in acylation. Therefore, the developed process is characterized by high atomic efficiency. Moreover, it was shown that acylation using geminal diacetates resulted in remarkable regioselectivity by discriminating among the primary and secondary hydroxyl groups in 1-phenyl-1,3-propanediol providing exclusively 3-acetoxy-1-phenyl-propan-1-ol in good yield. Further, enzymatic kinetic resolution (EKR) and chemoenzymatic dynamic kinetic resolution (DKR) protocols were developed using geminal diacetate as an acylating agent, resulting in chiral acetates in high yields up to 94% with enantiomeric excesses exceeding 99%.

Activity and specificity studies of the new thermostable esterase EstDZ2

In this paper, we study the activity and specificity of EstDZ2, a new thermostable carboxyl esterase of unknown function, which was isolated from a metagenome library from a Russian hot spring. The biocatalytic reaction employing EstDZ2 proved to be an efficient method for the hydrolysis of aryl p-, o- or m-substituted esters of butyric acid and esters of secondary alcohols. Docking studies revealed structural features of the enzyme that led to activity differences among the different substrates.