21382-98-9 Usage
Description
4-(METHYLTHIO)BENZONITRILE, also known as 4-(methylthio)benzonitrile, is an organic compound with the chemical formula C8H7NS. It is characterized by its distinct structure, which includes a benzene ring with a nitrile group, a methylthio group, and a cyano group. 4-(METHYLTHIO)BENZONITRILE has been investigated for its unique properties and potential applications in various fields.
Uses
Used in Chemical Synthesis:
4-(METHYLTHIO)BENZONITRILE is used as a chemical intermediate for the preparation of 4-cyanobenzenethiol. This application is significant because 4-cyanobenzenethiol can be further utilized in the synthesis of various organic compounds and materials.
Used in Surface-enhanced Raman Scattering (SERS) Studies:
In the field of analytical chemistry, 4-(METHYLTHIO)BENZONITRILE is used as a probe molecule for studying surface-enhanced Raman scattering (SERS) on silver surfaces. The compound's adsorption on silver surfaces has been investigated to understand its interaction with the surface and the resulting enhancement of Raman signals. This research is crucial for developing advanced sensing techniques and improving the detection of various molecules in complex samples.
Synthesis Reference(s)
Synthetic Communications, 14, p. 215, 1984 DOI: 10.1080/00397918408060724
Check Digit Verification of cas no
The CAS Registry Mumber 21382-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,3,8 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21382-98:
(7*2)+(6*1)+(5*3)+(4*8)+(3*2)+(2*9)+(1*8)=99
99 % 10 = 9
So 21382-98-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NS/c1-10-8-4-2-7(6-9)3-5-8/h2-5H,1H3
21382-98-9Relevant articles and documents
Diaryl-substituted (Dihydro)pyrrolo[3,2,1- hi ]indoles, a class of potent COX-2 inhibitors with tricyclic core structure
Laube, Markus,Gassner, Cemena,Sharma, Sai Kiran,Günther, Robert,Pigorsch, Arne,K?nig, Jonas,K?ckerling, Martin,Wuest, Frank,Pietzsch, Jens,Kniess, Torsten
, p. 5611 - 5624 (2015)
A new compound class of diaryl-substituted heterocycles with tricyclic dihydropyrrolo[3,2,1-hi]indole and pyrrolo[3,2,1-hi]indole core structures has been designed and was synthesized by a modular sequence of Friedel-Crafts acylation, amide formation, and
Nickel-Catalyzed Reversible Functional Group Metathesis between Aryl Nitriles and Aryl Thioethers
Delcaillau, Tristan,Boehm, Philip,Morandi, Bill
supporting information, p. 3723 - 3728 (2021/04/07)
We describe a new functional group metathesis between aryl nitriles and aryl thioethers. The catalytic system nickel/dcype is essential to achieve this fully reversible transformation in good to excellent yields. Furthermore, the cyanide- and thiol-free reaction shows high functional group tolerance and great efficiency for the late-stage derivatization of commercial molecules. Finally, synthetic applications demonstrate its versatility and utility in multistep synthesis.
N-bromosuccinimide/HCl mediated reduction of sulfoxides to sulfides
Wang, Jianqiang,Shi, Fangmin,Dai, Dongyan,Xiong, Liping,Yang, Yongpo
supporting information, p. 439 - 443 (2021/02/03)
An efficient reduction of sulfoxides to sulfides mediated by N-bromosuccinimide (NBS)/HCl system has been developed. This protocol shows good functional group compatibility as well as broad substrates scope with operational simplicity.