217447-49-9

Basic information

• Product Name: Methyl (2R,3R)-5,5-dimethoxy-2-[N,N'-(dibenzylcarbonylhydrazino)]-3-hydroxypentanoate
• Synonyms: Methyl (2R,3R)-5,5-dimethoxy-2-[N,N'-(dibenzylcarbonylhydrazino)]-3-hydroxypentanoate
• CAS NO: 217447-49-9
• Molecular Weight: 490.51
• Mol File: 217447-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl (2R,3R)-5,5-dimethoxy-2-[N,N'-(dibenzylcarbonylhydrazino)]-3-hydroxypentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (2R,3R)-5,5-dimethoxy-2-[N,N'-(dibenzylcarbonylhydrazino)]-3-hydroxypentanoate(217447-49-9)
• EPA Substance Registry System: Methyl (2R,3R)-5,5-dimethoxy-2-[N,N'-(dibenzylcarbonylhydrazino)]-3-hydroxypentanoate(217447-49-9)

Safety Data

• Hazardous Substances Data: 217447-49-9(Hazardous Substances Data)

Upstream product

• 217447-41-1 methyl 5,5-dimethoxy-3-oxo-4-pentanoate 

Downstream Products

• 217447-51-3 C₃₀H₄₄N₂O₉Si 
• 496841-09-9 (2R,3R)-3-Hydroxy-pyrrolidine-2-carboxylic acid methyl ester; compound with trifluoro-acetic acid 
• 119677-21-3 (2R,3R)-3-hydroxypyrrolidine-2-carboxylic acid 
• 217447-50-2 (3R,4R)-4-Hydroxy-2,3,4,5-tetrahydro-pyridazine-3-carboxylic acid methyl ester 

Relevant articles and documents

Rapid asymmetric synthesis of highly functionalized C5 chiral synthons. Practical preparation of trans-3 -hydroxy-D-proline

A stereocontrolled synthesis of (2R, 3R)-3-hydroxyproline 5 has been achieved in 33% overall yield from a prochiral β-ketoester : the methyl 5,5-dimethoxy-3-oxopentanoate 6. The key intermediate is the richly functionalized compound 4 which presented three different oxygenated groups and an anti relationship between the alcohol and the amine.