229-67-4Relevant articles and documents
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Loader,Timmons
, p. 1078,1081 (1966)
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Cu(II)-Catalyzed Construction of Heterobiaryls using 1-Diazonaphthoquinones: A General Strategy for the Synthesis of QUINOX and Related P,N Ligands
Biswas, Aniruddha,Pan, Subarna,Samanta, Rajarshi
supporting information, p. 1631 - 1636 (2022/03/14)
An efficient and straightforward method was developed for the synthesis of heterobiaryls using easily available N-oxides and diazonaphthoquinones under cheap Cu(II) catalysis. The developed method offered QUINOX and related congeners in a simple manner. A wide scope of important heterobiaryls was achieved with high site selectivity. The synthesized naphthols were transformed into the privileged related P,N ligands. Suitable resolution methods can directly afford the corresponding axially chiral heterobiaryls.
Light-induced carbocyclization of iodoalkenes
Campos-Gómez, Esther,Campos, Pedro J.,González, Héctor F.,Rodríguez, Miguel A.
experimental part, p. 4292 - 4295 (2012/07/16)
The direct irradiation of iodoalkenes leads to the formation of carbon-centered radical by homolysis of the C-I bond. The photoreaction is used in cyclizations with formation of six membered rings.
Preparation of polycyclic azaarenes by an extended Pomeranz-Fritsch procedure
Hewlins, Michael J. E.,Salter, Rhys
, p. 2157 - 2163 (2008/03/28)
An extension of the Pomeranz-Fritsch procedure has been evaluated as a route to some polycyclic azaarenes. Aromatic aldehydes were treated with the dimethyl and diethyl acetals of 2-aminoethanal, the resulting imines reduced to amines which were tosylated and the resulting sulfonamides treated under a range of acidic conditions. The two naphthaldehydes led to benzo[f]isoquinoline and benzo[h]isoquinoline in overall yields of 13% and 36%. Phenanthrene-9- carbaldehyde and phenanthrene-3-carbaldehyde gave dibenzo[f,h]isoquinoline and naphtho[2,1-g]isoquinoline, respectively, as the major tetracyclic products. No pentacyclic product was obtained from a similar sequence starting from pyrene-1-carbaldehyde. Georg Thieme Verlag Stuttgart.
