23210-25-5

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-1,3-diphenyl-
• CAS NO: 23210-25-5
• Molecular Formula: C20H15NO
• Molecular Weight: 285.345
• Mol File: 23210-25-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-1,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-1,3-diphenyl-(23210-25-5)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-1,3-diphenyl-(23210-25-5)

Safety Data

• Hazardous Substances Data: 23210-25-5(Hazardous Substances Data)

Upstream product

• 1636897-36-3 1,3-dihydro-3-nitro-1,3-diphenyl-2H-indol-2-one 
• 611-73-4 Benzoylformic acid 
• 122-39-4 diphenylamine 
• 100-52-7 benzaldehyde 
• 25438-37-3 phenyl(trimethylsiloxy)acetonitrile 
• 4358-87-6 (RS)-methyl mandelate 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 591-50-4 iodobenzene 
• 36147-01-0 1,3-diphenyl-3-hydroxy-1,3-dihydro-2H-indol-2-one 
• 723-89-7 1-phenyl-indole-2,3-dione 
• 91-56-5 indole-2,3-dione 
• 108-86-1 bromobenzene 
• 3335-98-6 1-phenyl-1,3-dihydro-indol-2-one 
• 108-90-7 chlorobenzene 

Downstream Products

• 36147-01-0 1,3-diphenyl-3-hydroxy-1,3-dihydro-2H-indol-2-one 
• 1636897-36-3 1,3-dihydro-3-nitro-1,3-diphenyl-2H-indol-2-one 
• 1636897-37-4 1,3-dihydro-3-hydroxy-6-nitro-1,3-diphenyl-2H-indol-2-one 
• 1636897-38-5 1,1’,3,3’-tetrahydro-1,1’,3,3’-tetraphenyl-2H,2’H-3,3’-biindole-2,2’-dione 
• 1352614-39-1 C₂₈H₂₃NO₃S 
• 1311959-01-9 3-chloro-1,3-diphenylindolin-2-one 
• 20538-11-8 1,3-diphenyl-1H-indole 
• 136368-96-2 3-hydroperoxy-1,3-diphenylindolin-2-one 

Relevant articles and documents

Silyl Cyanopalladate-Catalyzed Friedel-Crafts-Type Cyclization Affording 3-Aryloxindole Derivatives

3-Aryloxindole derivatives were synthesized through a Friedel-Crafts-type cyclization. The reaction was catalyzed by a trimethylsilyl tricyanopalladate complex generated in situ from trimethylsilyl cyanide and Pd(OAc) 2. Wide varieties of diethyl phosphates derived from N -arylmandelamides were converted almost quantitatively into oxindoles. When N, N -dibenzylamide was used instead of an anilide substrate, a benzo-fused δ-lactam was obtained. An oxindole product was subjected to substitution reactions to afford 3,3-diaryloxindoles with two different aryl groups.

Enantioselective Arylation of Oxindoles Using Modified BI-DIME Ligands

The Pd-catalyzed 3-arylation of 2-oxindoles with aryl bromides, chlorides and triflates is found to proceed using i -Pr-BI-DIME and Me 2 -BI-DIME ligands. The mono-arylation of 3-unsubstituted oxindoles is accomplished using a Pd 2 (dba) 3 / i -Pr-BI-DIME catalyst system, and gives good yields of 3-aryloxindoles from aryl bromides and chlorides. The arylation of 3-substituted oxindoles is also possible using this catalyst/ligand system. The asymmetric arylation of 3-substituted oxindoles is accomplished using Me 2 -BI-DIME to furnish oxindoles bearing a quaternary C-3 stereocenter in enantiomeric ratios of up to 93:7.

Reduction of 3-aminoquinoline-2,4(1H,3H)-diones and deamination of the reaction products

3-Aminoquinoline-2,4-diones were stereoselectively reduced with NaBH 4 to give cis-3-amino-3,4-dihydro-4-hydroxyquinolin-2(1H)-ones. Using triphosgene (=bis(trichloromethyl) carbonate), these compounds were converted to 3,3a-dihydrooxazolo[4,5-