2362-73-4

Basic information

• Product Name: 2-phenylcyclopentanol
• Synonyms: 2-phenylcyclopentanol
• CAS NO: 2362-73-4
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• Mol File: 2362-73-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 277.8°Cat760mmHg
• Flash Point: 104.2°C
• Appearance: /
• Density: 1.082g/cm³
• Vapor Pressure: 0.00213mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 2-phenylcyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylcyclopentanol(2362-73-4)
• EPA Substance Registry System: 2-phenylcyclopentanol(2362-73-4)

Safety Data

• Hazardous Substances Data: 2362-73-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O/c12-11-8-4-7-10(11)9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2

Upstream product

• 1026065-85-9 (1R,2R)-cis-2-Phenylcyclopentyl (R)-mandelate ester 
• 42086-64-6 trans-2-phenylcyclopentan-1-ol 
• 98-88-4 benzoyl chloride 
• 108-05-4 vinyl acetate 
• 2362-73-4 (+/-)-cis-2-phenylcyclopentanol 
• 97-72-3 2-Methylpropionic anhydride 
• 6226-35-3 (2-Cyclopropyl-2-phenyl-ethyl)-tosylat 
• 1198-34-1 2-Phenylcyclopentanone 
• 825-54-7 cyclopent-1-en-1-ylbenzene 
• 38805-89-9 (1S,2R)-2-phenylcyclopentanol 
• 285-67-6 Cyclopentene oxide 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 676552-21-9 (1R,2R)-2-phenylcyclopentyl acetate 
• 2362-73-4 (1R,2R)-(-)-cis-2-Phenylcyclopentanol 
• 676464-38-3 (+)-(1S,2S)-2-phenyl-1-cyclopentanol 
• 1026065-85-9 (1R,2R)-cis-2-Phenylcyclopentyl (R)-mandelate ester 
• 676464-29-2 (1S,2R)-2-phenylcyclopentanamine 
• 1198-34-1 2-Phenylcyclopentanone 

Relevant articles and documents

(Poly)cationic λ3-Iodane-Mediated Oxidative Ring Expansion of Secondary Alcohols

Herein, a simplified approach to the synthesis of medium-ring ethers through the electrophilic activation of secondary alcohols with (poly)cationic λ3-iodanes (N-HVIs) is reported. Excellent levels of selectivity are achieved for C–O bond migration over established α-elimination pathways, enabled by the unique reactivity of a novel 2-OMe-pyridine-ligated N-HVI. The resulting hexafluoroisopropanol (HFIP) acetals are readily derivatized with a range of nucleophiles, providing a versatile functional handle for subsequent manipulations. The utility of this methodology for late-stage natural product derivatization was also demonstrated, providing a new tool for diversity-oriented synthesis and complexity-to-diversity (CTD) efforts. Preliminary mechanistic investigations reveal a strong effect of alcohol conformation on the reactive pathway, thus providing a predictive power in the application of this approach to complex molecule synthesis.

Kinetic resolution of secondary alcohols catalyzed by chiral phosphoric acids

Acid instead of base: Kinetic resolution of secondary alcohols is realized using chiral Bronsted acid catalyzed acylation instead of the conventional basic conditions. A broad range of functional groups are tolerated, such as aldehydes, carboxylic acids, and enoates. The selectivity factor (s) reaches up to 215 at ambient temperature. Copyright

Diastereoselective reduction of alkenylboronic esters as a new method for controlling the stereochemistry of up to three adjacent centers in cyclic and acyclic molecules

(figure presented) cis-Boronates are readily available via a diastereoselective Pd-catalyzed reduction of tetrasubstituted alkenylboronic esters using H2. Applying the reaction conditions presented to unsaturated open-chain boronic esters allows the stereochemistry of up to three adjacent centers to be controlled.