2403-53-4

Basic information

• Product Name: 2-(4-nitrophenyl)-1,3-dioxolane
• Synonyms: 2-(p-Nitrophenyl)-1,3-dioxolane;4-Nitrobenzaldehyde ethylene acetal;2-(4-Nitrophenyl)-1,3-dioxolane 97%
• CAS NO: 2403-53-4
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.18
• Mol File: 2403-53-4.mol
• Article Data: 89

Chemical Properties

• Melting Point: 90.5 °C
• Boiling Point: 332.9 °C at 760 mmHg
• Flash Point: 164.7 °C
• Appearance: /
• Density: 1.329 g/cm³
• Vapor Pressure: 0.000273mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-(4-nitrophenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenyl)-1,3-dioxolane(2403-53-4)
• EPA Substance Registry System: 2-(4-nitrophenyl)-1,3-dioxolane(2403-53-4)

Safety Data

• Hazardous Substances Data: 2403-53-4(Hazardous Substances Data)

Usage

General Description

2-(4-nitrophenyl)-1,3-dioxolane is a chemical compound that belongs to the class of dioxolanes, which are cyclic organic compounds containing two oxygen atoms and four carbon atoms. It is also known as 4-Nitrophenyl-1,3-dioxolane, and it has a nitro group attached to the phenyl ring. This chemical is primarily used as a solvent in various industrial applications, including pharmaceuticals, agrochemicals, and electronics. It is also used as a reagent in organic synthesis and as an intermediate in the production of other chemicals. 2-(4-nitrophenyl)-1,3-dioxolane is a colorless liquid with a sweet, floral odor, and it is considered to be a flammable and potentially hazardous substance that should be handled with care.

InChI:InChI=1/C9H9NO4/c11-10(12)8-3-1-7(2-4-8)9-13-5-6-14-9/h1-4,9H,5-6H2

Upstream product

• 108212-53-9 2-<(4-nitrophenyl)methoxy>ethanol 
• 619-73-8 4-nitrobenzyl chloride 
• 107-21-1 ethylene glycol 
• 555-16-8 4-nitrobenzaldehdye 
• 881-67-4 4-nitrobenzaldehyde dimethyl acetal 
• 75-21-8 oxirane 
• 2403-62-5 p-nitrobenzaldehyde diethyl acetal 
• 7381-30-8 2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane 
• 22391-06-6 2-(4-nitrophenyl)-1,3-oxathiolane 
• 2916-31-6 2,2-dimethyl-1,3-dioxolane 
• 111-90-0 ethoxyethoxyethanol 
• 39184-67-3 3-chloro-3-(p-nitrophenyl)diazirine 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 24588-74-7 4-nitrophenyl-1,3-dithiane 
• 1253582-61-4 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-formylphenylcarbamoyl)-propyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253582-43-2 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-formylphenylcarbamoyl)-phenyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253582-02-3 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-(1,3-dioxolan-2-yl)-phenylcarbamoyl)propyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253582-42-1 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-(1,3-dioxolan-2-yl)-phenylcarbamoyl)phenyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253580-01-6 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-phenylcarbamoyl)propyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253582-03-4 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-{[(R)-2-(tert-butyldimethyl-silanyloxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-phenylcarbamoyl)propyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 1253582-44-3 biphenyl-2-ylcarbamic acid 1-(2-{[3-(4-{[(R)-2-(tert-butyldimethylsilanyloxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]-methyl}phenylcarbamoyl)phenyl]methylcarbamoyl}ethyl)piperidin-4-yl ester 
• 866327-13-1 4-(4H-dithieno[3,2-b:2',3'-d]pyrrol-4-yl)benzaldehyde 

Relevant articles and documents

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Application of poly(Vinylbenzyltrimethylammonium tribromide) resin as an efficient polymeric catalyst in the acetalization and diacetylation of benzaldehydes

The applications of a new supported tribromide reagent (poly(vinylbenzyltrimethylammonium tribromide) resin) were reported. This supported tribromide resin was used as a catalyst in the acetalization and diacetylation of benzaldehydes under mild conditions with high efficiency. The effects of solvents, and amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of acetal and 1,1-diacetates of benzaldehydes were selectively obtained in excellent yields.

Palladium-Catalyzed Mizoroki-Heck Reaction of Nitroarenes and Styrene Derivatives

We have developed a Mizoroki-Heck reaction of nitroarenes with alkenes under palladium catalysis. The use of a Pd/BrettPhos catalyst promoted the alkenylation, whereas other catalysts led to a decrease in the product yield. In addition to nitroarenes, nitroheteroarenes were also applicable to the present reaction. The combination of a nucleophilic aromatic substitution (SNAr) with the denitrative alkenylation produced a multifunctionalized arene in a one-pot operation.