2403-62-5

Basic information

• Product Name: 1-(diethoxymethyl)-4-nitrobenzene
• Synonyms: 1-(Diethoxymethyl)-4-nitrobenzene; benzene, 1-(diethoxymethyl)-4-nitro-
• CAS NO: 2403-62-5
• Molecular Formula: C₁₁H₁₅NO₄
• Molecular Weight: 225.2411
• Mol File: 2403-62-5.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 298.3°C at 760 mmHg
• Flash Point: 116.6°C
• Density: 1.142g/cm³
• Vapor Pressure: 0.00227mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: 1-(diethoxymethyl)-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(diethoxymethyl)-4-nitrobenzene(2403-62-5)
• EPA Substance Registry System: 1-(diethoxymethyl)-4-nitrobenzene(2403-62-5)

Safety Data

• Hazardous Substances Data: 2403-62-5(Hazardous Substances Data)

Usage

Physical state

Yellow solid

Molecular weight

207.21 g/mol

Uses

a. Production of pharmaceuticals
b. Intermediate in organic synthesis

Safety precautions

a. Potential irritant to skin, eyes, and respiratory system
b. Harmful if swallowed or inhaled
c. Store and handle in a well-ventilated area
d. Use appropriate personal protective equipment (PPE)

Upstream product

• 64-17-5 ethanol 
• 555-16-8 4-nitrobenzaldehdye 
• 873376-62-6 triethoxyantimony 
• 998-30-1 Triethoxysilane 
• 122-51-0 orthoformic acid triethyl ester 
• 75-52-5 nitromethane 
• 167261-43-0 (S)-2-amino-3-methyl-N-(pyridin-2-yl)butanamide 
• 78-94-4 methyl vinyl ketone 
• 881-67-4 4-nitrobenzaldehyde dimethyl acetal 
• 4578-68-1 ethoxy-p-nitrophenylacetic acid 
• 99-99-0 1-methyl-4-nitrobenzene 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 1945-24-0 1,1,3-Triethoxy-2-brom-3-(p-nitrophenyl)-propan 
• 555-16-8 4-nitrobenzaldehdye 
• 23837-16-3 ((4-nitrophenyl)methylene)bis(phenylsulfane) 
• 22391-06-6 2-(4-nitrophenyl)-1,3-oxathiolane 
• 881-67-4 4-nitrobenzaldehyde dimethyl acetal 
• 4578-70-5 p-nitrobenzaldehyde ethyl-methyl acetal 
• 72581-74-9 (1S,4R)-7,7-Dimethyl-1-[(2S,3S)-3-(4-nitro-phenyl)-oxaziridine-2-sulfonylmethyl]-bicyclo[2.2.1]heptan-2-one 
• 72538-30-8 (1S,4R)-7,7-Dimethyl-1-[(2R,3R)-3-(4-nitro-phenyl)-oxaziridine-2-sulfonylmethyl]-bicyclo[2.2.1]heptan-2-one 
• 41159-02-8 2-(4-nitrophenyl)-1,3-dithiolane 
• 16837-06-2 p-(3,3,4,4-tetramethyl-2,5-dioxa-1-borolyl)nitrobenzene 
• 2403-53-4 2-(4-nitrophenyl)-1,3-dioxolane 
• 36176-89-3 N-(p-nitrobenzylidene)benzenesulfonamide 
• 86428-23-1 3-(4-nitrophenyl)-2-(phenylsulfonyl)-1,2-oxaziridine 
• 55629-54-4 p-nitrobenzylidenecyanoacetamide 

Relevant articles and documents

Biomimetic Total Synthesis of Enterocin

The first chemical total synthesis of the highly oxygenated polyketide enterocin has been accomplished. The key step of the synthesis was a late-stage biomimetic reaction cascade involving two intramolecular aldol reactions in which each step proceeded in 52 % yield (averaged) and which established four of the seven stereogenic centers. The pivotal precursor for the cascade reaction was assembled from three readily available building blocks. A chiral dithioacetal with two stereogenic centers originating from L-arabinose represented the core fragment to both ends of which the other building blocks were attached by aldol reactions. The remaining stereogenic center was installed by Davis oxygenation immediately prior to the key step.

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

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α-Chymotrypsin-Induced Acetalization of Aldehydes and Ketones with Alcohols

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