24136-23-0 Usage
Description
4-Chloro-alpha-[3-(trifluoromethyl)phenoxy]benzeneacetic acid 2-(acetylamino)ethyl ester, also known as MBX 102, is a chemical compound with a complex structure that has been synthesized for specific applications in the pharmaceutical industry. It possesses unique properties that make it a promising candidate for various therapeutic uses.
Uses
Used in Pharmaceutical Industry:
4-Chloro-alpha-[3-(trifluoromethyl)phenoxy]benzeneacetic acid 2-(acetylamino)ethyl ester is used as a new medication for the treatment and prevention of acute gouty flares. It is particularly effective in managing the severe pain and inflammation associated with gout attacks, providing relief to patients suffering from this condition.
Additionally, MBX 102 is used as a URAT 1 inhibitor, which plays a crucial role in the regulation of uric acid levels in the body. By inhibiting the URAT 1 transporter, this compound helps to reduce the accumulation of uric acid, thereby preventing the formation of urate crystals and the subsequent development of gout.
Check Digit Verification of cas no
The CAS Registry Mumber 24136-23-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,3 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 24136-23:
(7*2)+(6*4)+(5*1)+(4*3)+(3*6)+(2*2)+(1*3)=80
80 % 10 = 0
So 24136-23-0 is a valid CAS Registry Number.
24136-23-0Relevant articles and documents
DCC Mediated Coupling for Halofenate Manufacture
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Paragraph 0063-0065, (2014/08/06)
The present application discloses a process for the preparation of a halofenate compound of the formula (III) or a salt thereof: wherein R, X and X′ are as defined herein, the process comprising contacting a compound of formula (Ia) with a compound of formula (Ib) and N,N′-dicyclohexylcarbodiimide under conditions sufficient to form the compound of formula (III).
PROCESS FOR THE PREPARATION OF (-)-(4-CHLORO-PHENYL)-(3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID 2-ACETYLAMINO-ETHYL ESTER
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Page/Page column 37-38, (2009/10/30)
The present invention is directed to a novel process for the preparation of (4-chloro-phenyl)-(3-thfluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester, useful in the treatment of metabolic disorders and further to a process for the preparation of (4-chloro-phenyl)-(3-thfluoromethyl-phenoxy)-acetic acid, a synthesis intermediate.
METHODS FOR AVOIDING EDEMA IN THE TREATMENT OR PREVENTION OF PPARγ-RESPONSIVE DISEASES, INCLUDING CANCER
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Page/Page column 77-78, (2008/06/13)
Compounds, compositions, and methods of avoiding edema while treating or preventing PPARγ-mediated diseases, including cancer, using derivatives and prodrugs are provided.
