252903-25-6

Basic information

• Product Name: ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE
• Synonyms: ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE;ethyl 5-amino-1-phenethyl-1H-pyrazole-4-carboxylate
• CAS NO: 252903-25-6
• Molecular Formula: C₁₄H₁₇N₃O₂
• Molecular Weight: 259.3
• Mol File: 252903-25-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 431.355 °C at 760 mmHg
• Flash Point: 214.676 °C
• Appearance: /
• Density: 1.199 g/cm³
• CAS DataBase Reference: ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE(252903-25-6)
• EPA Substance Registry System: ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE(252903-25-6)

Safety Data

• Hazardous Substances Data: 252903-25-6(Hazardous Substances Data)

Usage

General Description

Ethyl 5-amino-1-phenethylpyrazole-4-carboxylate is a chemical compound with a complex molecular structure consisting of a phenethyl group, a pyrazole ring, and an ethyl carboxylate group. It is an organic compound that is commonly used in the field of medicinal chemistry for the synthesis of various pharmaceuticals and related compounds. This chemical may have potential applications in the development of drugs for the treatment of various diseases and ailments. Its unique structure and properties make it a valuable building block for the creation of novel substances with potential therapeutic benefits. Further research and exploration of the potential uses of ethyl 5-amino-1-phenethylpyrazole-4-carboxylate could lead to the discovery of new and effective medications.

Upstream product

• 156-51-4 2-phenethylhydrazine sulfate 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 
• 51-71-8 Phenelzine 
• 103-63-9 1-phenyl-2-bromoethane 
• 1260243-04-6 ethyl 5-amino-1H-pyrazole-4-carboxylate 

Downstream Products

• 1021498-17-8 5-(2-bromo-acetylamino)-1-phenethyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1338789-17-5 1-(2-phenylethyl)-6-thioxo-1,5,6,7-tetrahydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1338789-19-7 6-(methylthio)-1-(2-phenylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]-pyrimidin-4-one 
• 1338789-21-1 4-chloro-6-(methylthio)-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]-pyrimidine 
• 1338789-23-3 N-(3-chlorophenyl)-6-(methylthio)-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1338789-09-5 N-(3-fluorobenzyl)-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1338789-10-8 N-(3-chlorophenyl)-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1338789-08-4 4-chloro-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1338789-07-3 1-(2-phenylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1338789-15-3 ethyl 5-{[(benzoylamino)carbonothioyl]amino}-1-(2-phenylethyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

A Michael Equilibration Model to Control Site Selectivity in the Condensation toward Aminopyrazoles

A Michael equilibration model is presented to provide for site-selective pyrazole condensations between alkoxyacrylonitriles and hydrazines. Both pyrazole isomers were accessed with high selectivity by employment of kinetically or thermodynamically controlled conditions. Substrate scope and identification of Michael intermediates, as well as competitive pathways, support the presented mechanistic proposal. Sandmeyer derivatization provided site-selective access to fully substituted pyrazoles.

AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME

Provided are aminopyrazole derivatives, a process for the preparation thereof, and a composition for preventing or treating an ischemic disease containing the same. Since the aminopyrazole derivatives of the present invention can reduce an ischemic cell d