25977-23-5

Basic information

• Product Name: (5-METHYL-1,2,4-OXADIAZOL-3-YL)METHANOL
• Synonyms: (5-METHYL-1,2,4-OXADIAZOL-3-YL)METHANOL;CHEMBRDG-BB 4010305;(5-methyl-1,2,4-oxadiazol-3-yl)methanol(SALTDATA: FREE)
• CAS NO: 25977-23-5
• Molecular Formula: C₄H₆N₂O₂
• Molecular Weight: 114.1
• Mol File: 25977-23-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 248.2 °C at 760 mmHg
• Flash Point: 103.9 °C
• Appearance: /
• Density: 1.285 g/cm³
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: 1.497
• PKA: 12.07±0.10(Predicted)
• CAS DataBase Reference: (5-METHYL-1,2,4-OXADIAZOL-3-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (5-METHYL-1,2,4-OXADIAZOL-3-YL)METHANOL(25977-23-5)
• EPA Substance Registry System: (5-METHYL-1,2,4-OXADIAZOL-3-YL)METHANOL(25977-23-5)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 25977-23-5(Hazardous Substances Data)

Usage

General Description

(5-Methyl-1,2,4-oxadiazol-3-yl)methanol is a chemical compound with the molecular formula C4H6N2O2. It belongs to the oxadiazole family, which is known for its diverse biological activities. This particular compound is a white solid with a molecular weight of 114.10 g/mol. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and materials. Additionally, it has been studied for its potential pharmacological properties, including antimicrobial, antifungal, and antiviral activities. Overall, (5-Methyl-1,2,4-oxadiazol-3-yl)methanol is a versatile compound with promising applications in various industries.

InChI:InChI=1/C4H6N2O2/c1-3-5-4(2-7)6-8-3/h7H,2H2,1H3

Upstream product

• 40699-38-5 5-methyl-[1,2,4]oxadiazole-3-carboxylic acid ethyl ester 
• 1217428-98-2 ethyl 2-oximinooxamate 
• 108-24-7 acetic anhydride 
• 14337-43-0 ethyl 2-chloro-2-(hydroxyimino)acetate 

Downstream Products

• 959406-40-7 3-(bromomethyl)-5-methyl-1,2,4-oxadiazole 
• 1192-80-9 3-(chloromethyl)-5-methyl-1,2,4-oxadiazole 
• 1083300-23-5 5-methyl-1,2,4-oxadiazole-3-carboxaldehyde 

Relevant articles and documents

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL

The present invention relates to pharmaceutical compounds of the Formula (I), or a pharmaceutically acceptable salt or composition thereof, and methods of their use for the treatment of pain, respiratory conditions, as well as inhibiting the Transient Receptor Potential Al ion channel (TRPA1).