40699-38-5

Basic information

• Product Name: ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE
• Synonyms: ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE;1,2,4-Oxadiazole-3-carboxylic acid, 5-Methyl-, ethyl ester;Ethyl 5-methyl-1,2,4-oxadiazole-3-carbonate;5-Methyl-1,2,4-oxadiazole-3-carboxylic acid ethyl ester
• CAS NO: 40699-38-5
• Molecular Formula: C6H8N2O3
• Molecular Weight: 156.14
• Product Categories: Esters;Oxadiazoles & Thiadiazoles;Oxadiazoles & Thiadiazoles
• Mol File: 40699-38-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 33-35 °C
• Boiling Point: 238℃
• Flash Point: 98℃
• Appearance: /
• Density: 1.207
• Vapor Pressure: 0.043mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -4.07±0.10(Predicted)
• CAS DataBase Reference: ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE(40699-38-5)
• EPA Substance Registry System: ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE(40699-38-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 40699-38-5(Hazardous Substances Data)

Usage

General Description

Ethyl 5-methyl-1,2,4-oxadiazole-3-carboxylate is a chemical compound with the molecular formula C7H9N3O3. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical compounds. ETHYL5-METHYL-1,2,4-OXADIAZOLE-3-CARBOXYLATE is known for its potential medicinal properties and is often used as a starting material for the development of new drugs. It is also used as a key intermediate in the production of agrochemicals and organic compounds. Due to its versatile chemical properties, ethyl 5-methyl-1,2,4-oxadiazole-3-carboxylate plays a crucial role in the development of new pharmaceutical and agricultural products.

InChI:InChI=1/C6H8N2O3/c1-3-10-6(9)5-7-4(2)11-8-5/h3H2,1-2H3

Upstream product

• 134285-41-9 C₆H₁₀N₂O₄ 
• 1217428-98-2 ethyl 2-oximinooxamate 
• 108-24-7 acetic anhydride 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 623-49-4 ethyl cyanoformate 

Downstream Products

• 20615-94-5 potassium 5-methyl-1,2,4-oxadiazole-3-carboxylate 
• 25977-23-5 (5-methyl-1,2,4-oxadiazol-3-yl)methanol 
• 19703-92-5 5-methyl-[1,2,4]oxadiazole-3-carboxylic acid 

Relevant articles and documents

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

PHTHALAZINE DERIVATIVES, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF

The present invention provides a compound of formula I, a cis-trans isomer, an enantiomer, a diastereoisomer, a racemate, a solvate, a hydrate, or a pharmaceutical acceptable salt and ester thereof, a preparation method for preparing the same, a pharmaceutical composition comprising the same and a use of the compound as an α5-GABAA receptor regulator, wherein T, Z, A and Y are as defined in the description.