27828-71-3 Usage
Description
5-Hydroxynicotinic acid, a nicotinic acid analog, is a white to off-white to yellow solid with potential inhibitory effects on the metabolism of nicotinic acid by human platelets. It plays a significant role in the investigation of the hydroxylation mechanism of the flavoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO).
Uses
Used in Pharmaceutical Research:
5-Hydroxynicotinic acid is used as a research compound for investigating the hydroxylation mechanism of the flavoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO). This application aids in understanding the metabolic pathways and potential therapeutic targets related to nicotinic acid metabolism.
Used in Platelet Metabolism Studies:
5-Hydroxynicotinic acid is used as an inhibitor in the study of platelet metabolism, specifically in the context of nicotinic acid metabolism. Its inhibitory effect on human platelets can provide insights into the regulation of platelet function and its potential implications in various diseases and conditions.
Used in Chemical Synthesis:
As a nicotinic acid analog, 5-Hydroxynicotinic acid can be used as a starting material or intermediate in the synthesis of various chemical compounds, particularly those with potential pharmaceutical or biological applications. Its unique structure allows for further modification and exploration of its properties and potential uses in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 27828-71-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,8,2 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 27828-71:
(7*2)+(6*7)+(5*8)+(4*2)+(3*8)+(2*7)+(1*1)=143
143 % 10 = 3
So 27828-71-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)/p-1
27828-71-3Relevant articles and documents
NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS
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Page/Page column 115, (2008/06/13)
The invention is related to compound which comprises at least one radical C=Y, Y being O or S, and an oxidable and non protonable nitrogen atom N wherein the distance (d) between the at least one carbon atom of the radical group C=Y and the nitrogen atom, when oxidized, is comprised between 0.3 and 0.8 nanometers. The invention is related to new heterocyclic compounds defined by formula G, their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of neurodegenerative or Alzheimer disease.
5-hydroxy-3-piperidylidenemethane derivatives as spasmolytics.
Kawazu,Kanno,Saito,Tamaki
, p. 914 - 918 (2007/10/04)
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