290825-52-4

Basic information

• Product Name: Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate
• Synonyms: Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate;Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate 98%;Dimethyl[2-nitro-4-(trifluoromethyl)phenyl]malonate98%
• CAS NO: 290825-52-4
• Molecular Formula: C₁₂H₁₀F₃NO₆
• Molecular Weight: 321.2061096
• Product Categories: blocks;Carboxes
• Mol File: 290825-52-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 57-58°
• Boiling Point: 361.3°Cat760mmHg
• Flash Point: 172.3°C
• Appearance: /
• Density: 1.428g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate(290825-52-4)
• EPA Substance Registry System: Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate(290825-52-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 290825-52-4(Hazardous Substances Data)

Usage

Uses

Dimethyl 2-(2-nitro-4-trifluoromethylphenyl)malonate

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 108-59-8 malonic acid dimethyl ester 
• 65754-26-9 2-methyl-5-trifluoromethylnitrobenzene 
• 95-92-1 oxalic acid diethyl ester 
• 367-86-2 1-fluoro-2-nitro-4-trifluoromethyl-benzene 

Downstream Products

• 1735-89-3 6-trifluoromethyl-2-indolinone 
• 877766-73-9 3-[1-(2,4-dichlorobenzyl)-6-trifluoromethyl-1H-indazol-3-yl]-acrylic acid ethyl ester 
• 877768-84-8 H₂-gamendazole 
• 877766-45-5 (E)-3-(1-(2,4-dichlorobenzyl)-6-(trifluoromethyl)-1H-indazol-3-yl)acrylic acid 
• 877772-09-3 (1-(2,4-dichlorobenzyl)-6-(trifluoromethyl)-1H-indazol-3-yl)methanol 
• 877768-41-7 3-[1-(2,4-dichlorobenzyl)-6-trifluoromethyl-1H-indazol-3-yl]-oxirane-2-carboxylic acid 
• 877773-21-2 1-(2,4-dichlorobenzyl)-6-(trifluoromethyl)-1H-indazole-3-carbaldehyde 
• 877766-37-5 methyl 1-(2,4-dichlorobenzyl)-6-(trifluoromethyl)-1H-indazole-3-carboxylate 
• 877773-19-8 2-(2,4-dichlorobenzyl)-6-trifluoromethyl-2H-indazole-3-carboxylic acid methyl ester 
• 877773-17-6 6-Trifluoromethyl-1H-indazole-3-carboxylic acid methyl ester 
• 877768-45-1 trans-2-[1-(2,4-dichloro-benzyl)-6-trifluoromethyl-1H-indazol-3-yl]-cyclopropanecarboxylic acid 
• 877766-69-3 3-[1-(2,4-dichlorobenzyl)-6-trifluoromethyl-1H-indazol-3-yl]-propionic acid ethyl ester 
• 1735-91-7 2-(2-nitro-4-(trifluoromethyl)phenyl)acetic acid 
• 13544-07-5 methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate 

Relevant articles and documents

LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT

Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject; inhibit spermatogenesis in the subject; reduce testis weight in the subject; reduce ovary weight in a female subject; reduce serum progesterone in the female subject; impair ovarian follicle function in the female subject; causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.

Lonidamine analogues and their use in male contraception and cancer treatment

Novel compounds useful for inhibiting spermatogenesis and cancer treatment, and in particular as inhibitors of heat shock proteins and/or elongation factor 1 alpha.

3-(PIPERAZINYLBENZYLIDENYL)-2-INDOLINONE COMPOUNDS AND DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS

-