294182-28-8

Basic information

• Product Name: 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine
• Synonyms: 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine
• CAS NO: 294182-28-8
• Molecular Weight: 362.121
• Mol File: 294182-28-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine(294182-28-8)
• EPA Substance Registry System: 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine(294182-28-8)

Safety Data

• Hazardous Substances Data: 294182-28-8(Hazardous Substances Data)

Upstream product

• 144025-04-7 (2,4-difluorophenyl)magnesium bromide 
• 348-57-2 2,4-difluorobromobenzene 
• 186581-53-3 diazomethane 
• 294182-06-2 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone 
• 294181-95-6 2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester 
• 624-28-2 2,5-dibromopyridine 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 1340593-79-4 (6-((2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridin-3-yl)boronic acid 
• 1340593-96-5 2-((2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)-5-(4-(trifluoromethoxy)phenyl)pyridine 
• 1357018-82-6 C₂₁H₁₂F₇NO 
• 1340593-90-9 C₂₀H₁₂F₅NO 
• 1340593-92-1 C₂₂H₁₄F₇NO₂ 
• 1357018-83-7 C₂₁H₁₂F₄N₂O 
• 1340593-89-6 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-(4-fluorophenyl)pyridin-2-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol 
• 1340593-91-0 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol 
• 1340593-95-4 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)-1-(5-(4-(trifluoromethoxy)phenyl)pyridin-2-yl)propan-2-ol 
• 1340593-97-6 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3-triazol-1-yl)-1-(5-(4-(trifluoromethoxy)phenyl)pyridin-2-yl)propan-2-ol 
• 1340593-61-4 4-(6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1H-tetrazol-1-yl)propyl)pyridin-3-yl)benzonitrile 
• 1340593-62-5 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(trifluoromethyl)phenyl)pyridin-2-yl)propan-2-ol 
• 1340593-80-7 C₂₃H₁₄F₉NO₂ 
• 1340593-69-2 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(trifluoromethoxy)phenyl)-pyridin-2-yl)propan-2-ol 

Relevant articles and documents

Deuterated azole alcohol compound, preparation method and uses thereof

The present invention discloses a deuterated azole alcohol compound represented by a formula (I), and a pharmaceutically acceptable salt thereof, a preparation method and uses thereof, and a prodrug.According to the present invention, the deuterated azole alcohol compound has good antifungal activity and good metabolic stability, and can be used for preparing antifungal drugs. The formula (I) isdefined in the specification.

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

ANTIFUNGAL COMPOUND PROCESS

The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.