2976-34-3

Basic information

• Product Name: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene
• Synonyms: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene;Methyl 2-nitrophenyl sulphone;Methyl 2-Nitrophenyl Sulfone
• CAS NO: 2976-34-3
• Molecular Formula: C₇H₇NO₄S
• Molecular Weight: 201.19978
• Mol File: 2976-34-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 106 °C
• Boiling Point: 403.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.406±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(2976-34-3)
• EPA Substance Registry System: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(2976-34-3)

Safety Data

• Hazardous Substances Data: 2976-34-3(Hazardous Substances Data)

Usage

General Description

2-(Methylsulphonyl)nitrobenzene and 1-(Methylsulphonyl)-2-nitrobenzene are both chemical compounds with similar structures. They belong to the class of nitrobenzenes and contain a methylsulphonyl group. These chemicals are commonly used in the production of dyes, pigments, and pharmaceuticals. They are also used in organic synthesis and as intermediates in the manufacturing of other chemicals. Both compounds are known for their potential toxicity and should be handled with caution. Overall, these chemicals have various industrial applications and are important intermediates in the synthesis of other chemical compounds.

Upstream product

• 13165-79-2 2-nitrobenzenesulfinic acid 
• 74-88-4 methyl iodide 
• 56075-38-8 1-(methylsulfonyl)-2-(2-nitrophenyl)diazene 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 62696-04-2 TBHP 
• 5906-99-0 2-nitrobenzenesulfonyl hydrazide 
• 609-73-4 o-nitroiodobenzene 
• 67-68-5 dimethyl sulfoxide 
• 50693-98-6 methyl 2-((2-nitrophenyl)thio)acetate 
• 6375-65-1 (2-nitro-phenylsulfanyl)-acetic acid 
• 4875-10-9 o-nitrothiophenol 
• 20277-69-4 sodium methansulfinate 
• 577-19-5 2-nitrophenyl bromide 
• 3058-47-7 methyl 2-nitrophenyl sulfide 

Downstream Products

• 27489-39-0 bis-(2-methanesulfonyl-phenyl)-diazene-N-oxide 
• 2987-49-7 2-(methylsulfonyl)aniline 
• 27489-32-3 N-(2-methanesulfonyl-phenyl)-hydroxylamine 
• 19111-44-5 α--phenylessigsaeure 
• 20628-27-7 N-(2-(methylsulfonyl)phenyl)acetamide 
• 824-39-5 sodium o-nitrophenate 
• 125106-55-0 o-mercaptophenyl methyl sulfone 
• 60036-47-7 o-methylsulphonylphenyl methyl sulphide 

Relevant articles and documents

Hydro/deutero deamination of arylazo sulfones under metal and (photo)catalyst-free conditions

Hydrodeaminated and monodeuterated aromatics were obtained via a visible-light driven reaction of arylazo sulfones. Deuteration occurs efficiently in deuterated media such as isopropanol-d8 or in THF-d8/water mixtures and exhibits a high tolerance to the nature and the position of the aromatic substituents.

Copper-catalyzed aerobic oxidation and cleavage/formation of C-S bond: A novel synthesis of aryl methyl sulfones from aryl halides and DMSO

With atmospheric oxygen as the oxidant, a novel copper(i)-catalyzed synthesis of aryl methyl sulfones from aryl halides and widely available DMSO is described. The procedure tolerates aryl halides with various functional groups (such as methoxy, acetyl, chloro, fluoro and nitro groups), which could afford aryl methyl sulfones in moderate to high yields. The copper-catalyzed aerobic oxidation and the cleavage/formation of C-S bond are the key steps for this transformation.

Asymmetric oxidation catalysis by a chiral Al(salalen) complex: Highly enantioselective oxidation of sulfides with aqueous hydrogen peroxide

(Chemical Equation Presented) Not afraid to get wet: Aluminum(salalen) complexes were found to be water compatible and therefore suitable catalysts for asymmetric oxidation with aqueous hydrogen peroxide. A variety of sulfides underwent the title reaction in the presence of the aluminum(salalen) complex shown to the give the desired sulfoxides with high to excellent enantioselectivity (see scheme; Bn = benzyl).