33491-02-0

Basic information

• Product Name: Benzene, 1-chloro-4-(chloroethynyl)-
• CAS NO: 33491-02-0
• Molecular Formula: C8H4Cl2
• Molecular Weight: 171.026
• Mol File: 33491-02-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-(chloroethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-(chloroethynyl)-(33491-02-0)
• EPA Substance Registry System: Benzene, 1-chloro-4-(chloroethynyl)-(33491-02-0)

Safety Data

• Hazardous Substances Data: 33491-02-0(Hazardous Substances Data)

Upstream product

• 19233-54-6 2-Chloro-1-(4-chloro-phenyl)-2-(triphenyl-λ⁵-phosphanylidene)-ethanone 
• 873-73-4 4-n-chlorophenylacetylene 
• 64-19-7 acetic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 1777-56-6 4-chlorobenzoylmethylenetriphenylphosphorane 
• 33491-03-1 1-(bromoethynyl)-4-chlorobenzene 
• 5263-17-2 4-chloro-1-(2,2-dichloroethenyl)benzene 

Downstream Products

• 830-39-7 1-chloro-4-pentachloroethyl-benzene 
• 101660-30-4 (1S,2S,5S,6R)-2,5-Dichloro-3,4-bis-(4-chloro-phenyl)-8-oxo-6-trifluoromethyl-7-oxa-tricyclo[4.2.2.0^2,5]deca-3,9-diene-9-carboxylic acid methyl ester 
• 51624-43-2 1-[4-(4-chlorophenyl)butane-1,3-diynyl]benzene 
• 1551098-94-2 C₁₄H₉Cl₃O₂S 
• 1551101-32-6 C₁₄H₉Cl₃O₂S 
• 70625-98-8 (Z)-2-Chloro-1-(4-chloro-phenyl)-3-phenyl-propenone 
• 1005500-80-0 N-((4-chlorophenyl)ethynyl)-N,4-dimethylbenzenesulfonamide 
• 178460-78-1 (S)-2-chloro-1-(4-chlorophenyl)ethan-1-ol 
• 142272-89-7 1-chloro-4-(ethoxyethynyl)benzene 
• 937-20-2 p-chlorophenacyl chloride 
• 7632-59-9 (Z)-1-chloro-4-(1,2-dichlorovinyl)benzene 
• 1313869-19-0 (Z)-2-chloro-1-(4-chlorophenyl)penta-1,4-dienyl acetate 
• 1314145-14-6 C₁₂H₉BrCl₂ 
• 1295508-59-6 C₁₁H₉BrCl₂O 

Relevant articles and documents

Transition-Metal-Free One-Step Synthesis of Ynamides

A robust transition-metal-free one-step strategy for the synthesis of ynamides from sulfonamides and (Z)-1,2-dichloroalkenes or alkynyl chlorides is presented. This method is not only effective for internal ynamides but also amenable for terminal ynamides. Various functional groups, even the vinyl moiety, are compatible, and thus, this strategy offers the opportunity for further functionalization.

Highly efficient and recyclable catalyst for the direct chlorination, bromination and iodination of terminal alkynes

Direct halogenation, including chlorination, bromination and iodination of terminal alkynes, are of great importance in organic synthesis. Here an efficient and recyclable nano-Ag/g-C3N4 catalyst system was developed and proved to be remarkably active with 39 examples varied from chlorination, bromination to iodination, of which 14 runs have yielded more than 95% of the product. Recycling of the catalyst was also achieved without obvious activity loss after several runs: 99% yield was observed even after 5 runs in the bromination of phenylacetylene. The catalysts system is of low cost and easy to be prepared, making this procedure versatile, convenient and economic.

Facile and efficient synthesis of 1-haloalkynes via DBU-mediated reaction of terminal alkynes and N-haloimides under mild conditions

Directly from terminal alkynes and with N-halosuccinimides (halo = Br and I) or N-cholorophthalimide as the halogen sources, DBU as the activator, 1-haloalkynes were prepared in good to excellent yields at room temperature. Bis(bromoalkyne) and bis(iodoal