34351-19-4 Usage
Description
(3S)-3-amino-1-chloro-4-phenyl-2-butanone hydrochloride is a versatile chemical compound belonging to the class of ketones. It features an amino group, a chloro group, and a phenyl group attached to a butanone backbone. This hydrochloride salt form enhances its solubility in water, making it advantageous for various applications.
Uses
Used in Organic Chemistry:
(3S)-3-amino-1-chloro-4-phenyl-2-butanone hydrochloride is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with different properties and functions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (3S)-3-amino-1-chloro-4-phenyl-2-butanone hydrochloride is utilized for the development of pharmaceuticals and bioactive molecules. Its presence of functional groups makes it a promising candidate for the design and synthesis of new drugs with potential therapeutic applications.
Used in Drug Development:
(3S)-3-amino-1-chloro-4-phenyl-2-butanone hydrochloride is employed in drug development as a key intermediate in the synthesis of various pharmaceutical agents. Its versatility and reactivity contribute to the creation of novel drug candidates with improved efficacy and safety profiles.
Used in Research:
(3S)-3-amino-1-chloro-4-phenyl-2-butanone hydrochloride is also used in research settings to study the structure-activity relationships of different molecules and to explore new chemical reactions and synthetic pathways. Its unique properties make it a valuable tool for advancing scientific knowledge and understanding in the fields of chemistry and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 34351-19-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,3,5 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 34351-19:
(7*3)+(6*4)+(5*3)+(4*5)+(3*1)+(2*1)+(1*9)=94
94 % 10 = 4
So 34351-19-4 is a valid CAS Registry Number.
34351-19-4Relevant articles and documents
Creation of an artificial metalloprotein with a Hoveyda-Grubbs catalyst moiety through the intrinsic inhibition mechanism of α-chymotrypsin
Matsuo, Takashi,Imai, Chie,Yoshida, Takefumi,Saito, Takashi,Hayashi, Takashi,Hirota, Shun
, p. 1662 - 1664 (2012/03/27)
An l-phenylalanyl chloromethylketone-based inhibitor equipped with a Hoveyda-Grubbs catalyst moiety was regioselectively incorporated into the cleft of α-chymotrypsin through the intrinsic inhibition mechanism of the protein to construct an artificial organometallic protein. The Royal Society of Chemistry 2012.
Process for producing alpha-aminoketones
-
, (2008/06/13)
An amino group of an α-amino acid ester is protected as an imine, and it is then reacted with a halomethyllithium to obtain an N-protected-α-aminohalomethylketone. Further, this N-protected-α-aminohalomethylketone is treated with an acid to obtain an α-aminohalomethylketone. This process is suited for industrial production, and can produce an α-aminohalomethylketone and its related compounds economically and efficiently.
Practical synthesis of α-aminoalkyl-α′-chloromethylketone derivatives. Part 2: Chloromethylation of N-imine-protected amino acid esters
Onishi, Tomoyuki,Nakano, Takashi,Hirose, Naoko,Nakazawa, Masakazu,Izawa, Kunisuke
, p. 5887 - 5890 (2007/10/03)
Chloromethylation of N-imine-protected amino acid esters followed by acid hydrolysis gave α-aminoalkyl-α′-chloromethylketone as a HCl salt form in good yield without racemization. The amino group was conveniently protected with carbamate protecting reagents to give various useful intermediates for the protease inhibitors.
