345580-18-9

Basic information

• Product Name: (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide
• Synonyms: (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide
• CAS NO: 345580-18-9
• Molecular Weight: 434.381
• Mol File: 345580-18-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide(345580-18-9)
• EPA Substance Registry System: (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide(345580-18-9)

Safety Data

• Hazardous Substances Data: 345580-18-9(Hazardous Substances Data)

Upstream product

• 530441-95-3 (R)-1-(1-(bromomethoxy)ethyl)-3,5-bis(trifluoromethyl)benzene 
• 345579-89-7 (R)-2-tert-butyl-3-methyl-(S)-5-phenylimidazolidin-4-one 
• 368-63-8 (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 129213-83-8 (S)-2-amino-N-methyl-2-phenylacetamide 
• 30071-93-3 3,5-bis(trifluoromethyl)phenyl methyl ketone 
• 618096-34-7 (S)-5-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxymethyl]-(R)-2-tert-butyl-3-methyl-5-phenylimidazolidin-4-one 

Downstream Products

• 345579-91-1 (S)-5-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxymethyl]-5-phenylimidazolidine-2,4-dione 
• 345578-66-7 (R)-4-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxymethyl]-4-phenyl-imidazolidin-2-one 

Relevant articles and documents

Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones: Potent NK1 Antagonists

(Equation presented) A highly efficient and practical synthesis of 4,4-Disubstituted-2-Imidazolidinones utilizing a "self-reproduction of the center of chirality" strategy is described.