345579-91-1

Basic information

• Product Name: 2,4-Imidazolidinedione, 5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenyl-, (5S)-
• CAS NO: 345579-91-1
• Molecular Formula: C20H16F6N2O3
• Molecular Weight: 446.349
• Mol File: 345579-91-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-Imidazolidinedione, 5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenyl-, (5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Imidazolidinedione, 5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenyl-, (5S)-(345579-91-1)
• EPA Substance Registry System: 2,4-Imidazolidinedione, 5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenyl-, (5S)-(345579-91-1)

Safety Data

• Hazardous Substances Data: 345579-91-1(Hazardous Substances Data)

Upstream product

• 618096-34-7 (S)-5-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxymethyl]-(R)-2-tert-butyl-3-methyl-5-phenylimidazolidin-4-one 
• 530441-95-3 (R)-1-(1-(bromomethoxy)ethyl)-3,5-bis(trifluoromethyl)benzene 
• 368-63-8 (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 
• 30071-93-3 3,5-bis(trifluoromethyl)phenyl methyl ketone 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 62861-51-2 phenacyl trifluoromethanesulfonate 
• 530441-99-7 2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethanone 
• 151-50-8 potassium cyanide 
• 506-87-6 ammonium carbonate 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 345580-18-9 (S)-2-amino-3-[(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-N-methyl-2-phenylpropionamide 

Downstream Products

• 345578-66-7 (R)-4-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxymethyl]-4-phenyl-imidazolidin-2-one 

Relevant articles and documents

Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions

A series of novel five-membered urea derivatives as potent NK1 receptor antagonists is described. The effects of substitution of a 4-fluoro group at the phenyl ring and the introduction of an α-methyl group at the benzylic position to improve p