35232-96-3Relevant articles and documents
Hypolipidemic activity of 6-substituted 6,7-dihydro-5H-dibenz[c,e]azepine and the effects of 6,7-dihydro-5H-dibenz[c,e]azepine on lipid metabolism of rodents
Hall,Murthy,Wyrick
, p. 622 - 626 (1986)
A series of 6-substituted derivatives of 6,7-dihydro-5H-dibenz[c,e]azepine was found to be active hypolipidemic agents in rodents at doses of mg/kg per day. The parent drug was found to suppress the enzyme activity of ATP-dependent citrate lyase, sn-glyce
An amine template strategy to construct successive C-C bonds: Synthesis of benzo[: H] quinolines by a deaminative ring contraction cascade
McFadden, Timothy Patrick,Nwachukwu, Chideraa Iheanyi,Roberts, Andrew George
, p. 1379 - 1385 (2022/03/01)
We developed a convergent strategy to build, cyclize and excise nitrogen from tertiary amines for the synthesis of polyheterocyclic aromatics. Biaryl-linked azepine intermediates can undergo a deaminative ring contraction cascade reaction, excising nitrogen with the formation of an aromatic core. This strategy and deaminative ring contraction reaction are useful for the synthesis of benzo[h]quinolines. This journal is
1,7-Electrocyclisation of non-stabilised α,β:y,o-unsaturated azomethine ylides
Arany, Andrea,Bendell, David,Groundwater, Paul W.,Garnett, Ian,Nyerges, Miklos
, p. 2605 - 2608 (2007/10/03)
The generation of α,β:γ,5-unsaturated azomethine ylides 8 is described, starting from TV-substituted α-amino acids 7 and aldehydes 6,12. These azomethine ylides undergo a 1,7-electrocyclisation, followed by a [l,5]-hydrogen shift, to give the dihydrobenza