35452-54-1

Basic information

• Product Name: Formamide, N-(4-bromophenyl)-N-methyl-
• CAS NO: 35452-54-1
• Molecular Formula: C8H8BrNO
• Molecular Weight: 214.062
• Mol File: 35452-54-1.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: Formamide, N-(4-bromophenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-(4-bromophenyl)-N-methyl-(35452-54-1)
• EPA Substance Registry System: Formamide, N-(4-bromophenyl)-N-methyl-(35452-54-1)

Safety Data

• Hazardous Substances Data: 35452-54-1(Hazardous Substances Data)

Upstream product

• 667-27-6 Ethyl bromodifluoroacetate 
• 6911-87-1 4-bromo-N-methylaniline 
• 124-38-9 carbon dioxide 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 32328-81-7 4-bromo-N-methylen-aniline 
• 64-18-6 formic acid 
• 106-40-1 4-bromo-aniline 
• 2617-78-9 N-(4-bromophenyl)formamide 
• 74-88-4 methyl iodide 
• 85462-16-4 N-Methyl-O-p-nitrophenylsulphonylhydroxylamine 
• 1122-91-4 4-bromo-benzaldehyde 
• 93-61-8 N-methyl-N-phenylformamide 

Downstream Products

• 180140-09-4 (E)-N,N'-Bis-(4-bromo-phenyl)-1,2-dichloro-N,N'-dimethyl-ethene-1,2-diamine 
• 535920-92-4 7-bromo-4-(4-bromophenyl)-1-methylbenzo[f][1,4]-diazepine-2,3-dicarboxylic anhydride 
• 1643531-64-9 (E)-tert-butyl 3-[N-(4-bromophenyl)-N-(methyl)amino]acrylate 
• 6911-87-1 4-bromo-N-methylaniline 
• 157671-45-9 2-[(4-bromophenyl)(methyl)amino]acetonitrile 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 180140-18-5 5,5'-Dibromo-N³,N^3'-bis-(4-bromo-phenyl)-1,1',N³,N^3'-tetramethyl-1H,1'H-[2,2']biindolyl-3,3'-diamine 
• 653605-07-3 8,8'-bis(5,11-dimethyl-5,6,11,12-tetrahydro-2-bromodibenzo[b,f][1,5]diazocine) 
• 2058-72-2 5-bromo-1-methyl-1H-indole-2,3-dione 

Relevant articles and documents

Method for preparing formamide compound by using MCOF to catalyze CO2 as carbon source at normal temperature and pressure

The invention provides a method for preparing a formamide compound by using MCOF to catalyze CO2 as a carbon source at normal temperature and pressure, and belongs to the technical field of chemistry and chemical engineering. Under the conditions of normal temperature and normal pressure, CO2 is used as a carbon source to realize N-formylation reaction of various amine substrates. The method has the advantages that the reaction system uses the metal ion-doped two-dimensional covalent organic framework MCOF as the catalyst, CO2 is reduced at normal temperature and normal pressure to provide acyl, high-pressure hydrogen and toxic CO are prevented from being used, and the reaction conditions are mild (normal temperature and normal pressure). According to the method for preparing the formamide, the greenhouse gas carbon dioxide serves as a carbon source, the cost is low, operation is easy, reaction conditions are mild (normal temperature and normal pressure), the yield of the prepared formamide product is excellent (99%), and a green synthesis method is provided for N-acylation reaction.

Synthesis of silyl formates, formamides, and aldehydesviasolvent-free organocatalytic hydrosilylation of CO2

Carbon dioxide (CO2) was used as a C1 source to prepare silyl formates, formamides, and aldehydes. Tetrabutylammonium acetate (TBAA) catalyzed the solvent-freeN-formylation of amines with CO2and hydrosilane to give formamides including Weinreb formamide, Me(MeO)NCHO, which was successively converted into aldehydes by one-pot reactions with Grignard reagents.

Catalyst-free selective: N -formylation and N -methylation of amines using CO2 as a sustainable C1 source

We herein describe catalyst-free selective N-formylation and N-methylation of amines using CO2 as a sustainable C1 source. By tuning the reaction solvent and temperature, the selective synthesis of formamides and methylamines is achieved in good to excellent yields using sodium borohydride (NaBH4) as a sustainable reductant.