36978-51-5 Usage
Description
5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is a phenylacetic acid derivative with the chemical formula C11H12O3. It is an aromatic compound that features an acetic acid attached to a phenyl group, with a methyl group bonded to the phenyl ring. 5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is a derivative of valeric acid, which has a five-carbon chain. It is utilized in the pharmaceutical industry for the production of various pharmaceuticals and can be found in natural sources like plants and essential oils. 5-(3-METHYLPHENYL)-5-OXOVALERIC ACID holds potential for biological applications and is under investigation in both pharmaceutical and chemical research fields.
Uses
Used in Pharmaceutical Industry:
5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is used as a key intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs and therapeutic agents. Its unique structure allows it to be a valuable component in the creation of molecules with specific biological activities.
Used in Chemical Research:
In the chemical industry, 5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is used as a subject of research to explore its properties and potential applications. This includes examining its reactivity, stability, and how it can be modified or combined with other compounds to create new materials or improve existing ones.
Used in Natural Product Extraction:
5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is found in some natural sources such as plants and essential oils. It is used in the extraction and purification processes to isolate this compound for use in various applications, including as a starting material for the synthesis of pharmaceuticals or other chemical products.
Used in Drug Development:
As a compound with potential biological applications, 5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is used in drug development for its possible contribution to the creation of new medications. Researchers are interested in its properties and how it can be utilized to address specific medical needs or improve the efficacy of existing treatments.
Overall, 5-(3-METHYLPHENYL)-5-OXOVALERIC ACID is a versatile compound with applications spanning across the pharmaceutical, chemical, and natural product industries, making it an important substance for ongoing research and development efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 36978-51-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,7 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 36978-51:
(7*3)+(6*6)+(5*9)+(4*7)+(3*8)+(2*5)+(1*1)=165
165 % 10 = 5
So 36978-51-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O3/c1-9-4-2-5-10(8-9)11(13)6-3-7-12(14)15/h2,4-5,8H,3,6-7H2,1H3,(H,14,15)
36978-51-5Relevant articles and documents
Direct Synthesis of Chiral NH Lactams via Ru-Catalyzed Asymmetric Reductive Amination/Cyclization Cascade of Keto Acids/Esters
Shi, Yongjie,Tan, Xuefeng,Gao, Shuang,Zhang, Yao,Wang, Jingxin,Zhang, Xumu,Yin, Qin
supporting information, p. 2707 - 2713 (2020/03/30)
Lactams with a stereogenic center adjacent to the N atom have existed in many medicinal agents and bioactive alkaloids. Herein we report a broadly applicable synthesis of enantioenriched NH lactams through a one-pot asymmetric reductive amination/cyclization sequence of easily available keto acids/esters. Such cascade processes alleviate the demand for protecting group manipulations as well as intermediate purification. This strategy is capable of constructing enantioenriched lactams and benzo-lactams of a five-, six-, or seven-membered ring in generally high yield and with excellent enantioselectivities (up to 97% ee). Scalable and concise syntheses of key drug intermediates have further displayed the importance of this methodology.
NEW CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF
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Page/Page column 45, (2012/01/14)
The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.
