374067-94-4

Basic information

• Product Name: Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate
• Synonyms: 4-(Aminosulfonyl)-a,a-dimethyl-benzeneacetic Acid Ethyl Ester;Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate;4-(Aminosulfonyl)-α,a-dimethyl-benzeneacetic Acid Ethyl Ester;4-(AMinosulfonyl)-α,α-diMethyl-benzeneacetic Acid Ethyl Ester
• CAS NO: 374067-94-4
• Molecular Formula: C₁₂H₁₇NO₄S
• Molecular Weight: 271.33
• Product Categories: Chemical Amines;Amines;Aromatics;Sulfur & Selenium Compounds;Amines, Aromatics, Sulfur & Selenium Compounds
• Mol File: 374067-94-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 68-71?C
• Boiling Point: 402.23°C at 760 mmHg
• Flash Point: 197.062°C
• Appearance: /
• Density: 1.225g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• PKA: 10.06±0.10(Predicted)
• CAS DataBase Reference: Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate(374067-94-4)
• EPA Substance Registry System: Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate(374067-94-4)

Safety Data

• Hazardous Substances Data: 374067-94-4(Hazardous Substances Data)

Usage

Description

Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate, with the CAS number 374067-94-4, is a brown solid compound that is primarily utilized in the field of organic synthesis. Its unique chemical structure allows it to serve as an essential building block for the creation of various complex organic molecules.

Uses

Used in Organic Synthesis:
Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate is used as a synthetic intermediate for the development of a wide range of organic compounds. Its chemical properties make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate is used as a key building block for the synthesis of various drug candidates. Its unique structure can be further modified to create new molecules with potential therapeutic applications.
Used in Agrochemical Industry:
Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate is also employed in the agrochemical industry as a starting material for the synthesis of novel pesticides and other crop protection agents. Its incorporation into these products can lead to the development of more effective and environmentally friendly solutions for agricultural challenges.
Used in Specialty Chemicals:
In the specialty chemicals sector, Ethyl 2-Methyl-2-(4-sulfamoylphenyl)propionate is used as a versatile intermediate for the production of various high-value chemicals. These can include additives, dyes, and other performance-enhancing compounds that are used across a wide range of industries.

InChI:InChI=1/C12H17NO4S/c1-4-17-11(14)12(2,3)9-5-7-10(8-6-9)18(13,15)16/h5-8H,4H2,1-3H3,(H2,13,15,16)

Upstream product

• 2901-13-5 ethyl 2-methyl-2-phenylpropionate 
• 321565-78-0 ethyl 2-(4-chlorosulfonylphenyl)-2-methylpropionate 

Downstream Products

• 374067-95-5 2-methyl-2-(4-sulfamoylphenyl)propionic acid 
• 374068-00-5 2-(4-(N-(5-acetoxymethyl)phenyl-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-N-acetylsulfamoyl)phenyl)-2-methylpropyl acetate 
• 245118-91-6 N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 374067-99-9 2-(4-(N-acetyl-N-(5-((4-bromomethyl)phenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate 
• 374067-98-8 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate 
• 245118-90-5 4-[1,1-dimethyl-2-(tetrahydro-pyran-2-yloxy)-ethyl]-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide 
• 169679-53-2 N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-(4-methylphenyl)-4-pyrimidinyl]-4-(2-hydroxy-1,1-dimethylethyl)-benzenesulfonamide 
• 245118-89-2 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 169677-37-6 2-(4-(N-(6-chloro-(2-hydroxyethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropionic acid 
• 374067-97-7 2-(4-(N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropionic acid 
• 245118-94-9 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 
• 374067-96-6 4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 

Relevant articles and documents

Potent and selective ET-A antagonists. 2. Discovery and evaluation of potent and water soluble N-(6-(2-(Aryloxy)ethoxy)-4-pyrimidinyl) sulfonamide derivatives

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